Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape

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Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape

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Title: Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape
Author: Whitesides, George M.; Cheng, Chao-Min; Mazzeo, Aaron D.; Gong, Jinlong; Martinez, Andres W.; Phillips, Scott T.; Jain, Nina

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Citation: Cheng, Chao-Min, Aaron D. Mazzeo, Jinlong Gong, Andres W. Martinez, Scott T. Phillips, Nina Jain, and George M. Whitesides. 2010. Millimeter-scale contact printing of aqueous solutions using a stamp made out of paper and tape. Lab on a Chip 10(23): 3201-3205.
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Abstract: This communication describes a simple method for printing aqueous solutions with millimeter-scale patterns on a variety of substrates using an easily fabricated, paper-based microfluidic device (a paper-based “stamp”) as a contact printing device. The device is made from inexpensive materials, and it is easily assembled by hand; this method is thus accessible to a wide range of laboratories and budgets. A single device was used to print over 2500 spots in less than three minutes at a density of 16 spots per square centimeter. This method provides a new tool to pattern biochemicals—reagents, antigens, proteins, and DNA—on planar substrates. The accuracy of the volume of fluid delivered in simple paper-to-paper printing is low, and although the pattern transfer is rapid, it is better suited for qualitative than accurate, quantitative work. By patterning the paper to which the transfer occurs using wax printing or an equivalent technique, accuracy increases substantially.
Published Version: doi:10.1039/C004903D
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:9871958

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  • FAS Scholarly Articles [7078]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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