Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape

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Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape

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dc.contributor.author Whitesides, George M.
dc.contributor.author Cheng, Chao-Min
dc.contributor.author Mazzeo, Aaron D.
dc.contributor.author Gong, Jinlong
dc.contributor.author Martinez, Andres W.
dc.contributor.author Phillips, Scott T.
dc.contributor.author Jain, Nina
dc.date.accessioned 2012-11-06T17:02:50Z
dc.date.issued 2010
dc.identifier.citation Cheng, Chao-Min, Aaron D. Mazzeo, Jinlong Gong, Andres W. Martinez, Scott T. Phillips, Nina Jain, and George M. Whitesides. 2010. Millimeter-scale contact printing of aqueous solutions using a stamp made out of paper and tape. Lab on a Chip 10(23): 3201-3205. en_US
dc.identifier.issn 1473-0197 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:9871958
dc.description.abstract This communication describes a simple method for printing aqueous solutions with millimeter-scale patterns on a variety of substrates using an easily fabricated, paper-based microfluidic device (a paper-based “stamp”) as a contact printing device. The device is made from inexpensive materials, and it is easily assembled by hand; this method is thus accessible to a wide range of laboratories and budgets. A single device was used to print over 2500 spots in less than three minutes at a density of 16 spots per square centimeter. This method provides a new tool to pattern biochemicals—reagents, antigens, proteins, and DNA—on planar substrates. The accuracy of the volume of fluid delivered in simple paper-to-paper printing is low, and although the pattern transfer is rapid, it is better suited for qualitative than accurate, quantitative work. By patterning the paper to which the transfer occurs using wax printing or an equivalent technique, accuracy increases substantially. en_US
dc.description.sponsorship Chemistry and Chemical Biology en_US
dc.language.iso en_US en_US
dc.publisher Royal Society of Chemistry en_US
dc.relation.isversionof doi:10.1039/C004903D en_US
dash.license OAP
dc.subject antigens en_US
dc.subject aqueous solutions en_US
dc.subject contact en_US
dc.subject density en_US
dc.subject devices en_US
dc.subject printing en_US
dc.subject spots en_US
dc.subject tools en_US
dc.subject adhesives en_US
dc.subject chemistry en_US
dc.subject chromatography en_US
dc.subject methods en_US
dc.subject coloring agents en_US
dc.subject DNA en_US
dc.subject equipment en_US
dc.subject design en_US
dc.subject materials en_US
dc.subject testing en_US
dc.subject microchip en_US
dc.subject analytical en_US
dc.subject procedures en_US
dc.subject instrumentation en_US
dc.subject paper proteins en_US
dc.subject reproducibility of results en_US
dc.subject surface properties en_US
dc.title Millimeter-Scale Contact Printing of Aqueous Solutions Using a Stamp Made Out of Paper and Tape en_US
dc.type Journal Article en_US
dc.description.version Accepted Manuscript en_US
dc.relation.journal Lab on a Chip en_US
dash.depositing.author Whitesides, George M.
dc.date.available 2012-11-06T17:02:50Z

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  • FAS Scholarly Articles [5138]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University

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