Brain Function and Chromatin Plasticity

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Brain Function and Chromatin Plasticity

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Title: Brain Function and Chromatin Plasticity
Author: Dulac, Catherine
Citation: Dulac, Catherine. 2010. Brain function and chromatin plasticity. Nature 465(7299): 728–735.
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Abstract: The characteristics of epigenetic control, including the potential for long-lasting, stable effects on gene expression that outlive an initial transient signal, could be of singular importance for post-mitotic neurons, which are subject to changes with short- to long-lasting influence on their activity and connectivity. Persistent changes in chromatin structure are thought to contribute to mechanisms of epigenetic inheritance. Recent advances in chromatin biology offer new avenues to investigate regulatory mechanisms underlying long-lasting changes in neurons, with direct implications for the study of brain function, behaviour and diseases.
Published Version: doi:10.1038/nature09231
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075582/
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:9888896

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  • FAS Scholarly Articles [7470]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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