%PDF-1.4
%
1 0 obj
<<
/Type /Catalog
/Version /1.6
/Pages 2 0 R
/PageLabels 3 0 R
/Metadata 4 0 R
/OpenAction 5 0 R
/Names 6 0 R
/Outlines 7 0 R
>>
endobj
8 0 obj
<<
/Creator (Apache FOP Version 2.4)
/Producer (Apache FOP Version 2.4)
/CreationDate (D:20240329090833-04'00')
/Author (Rohit Bakshi)
/Keywords (brain, cortical lesions, multiple sclerosis, cognition, brain atrophy, MRI, physical disability, spinal cord)
/ModDate (D:20160627145730+05'30')
/Subject (Objective: To test a new version of the Magnetic Resonance Disease Severity Scale \(v.3 = MRDSS3\) for multiple sclerosis \(MS\), incorporating cortical gray matter lesions \(CLs\) from 3T magnetic resonance imaging \(MRI\).)
/Title (The Contribution of Cortical Lesions to a Composite MRI Scale of Disease Severity in Multiple Sclerosis)
/Trapped /False
>>
endobj
2 0 obj
<<
/Type /Pages
/Kids [9 0 R 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R 16 0 R 17 0 R 18 0 R
19 0 R]
/Count 11
>>
endobj
3 0 obj
<<
/Nums [0 20 0 R]
>>
endobj
4 0 obj
<<
/Length 865
/Type /Metadata
/Subtype /XML
>>
stream
application/pdf
x-unknown
2024-03-29T09:08:33-04:00
Apache FOP Version 2.4
1.4
Apache FOP Version 2.4
2024-03-29T09:08:33-04:00
2024-03-29T09:08:33-04:00
endstream
endobj
5 0 obj
<<
/D [21 0 R /Fit]
/S /GoTo
>>
endobj
6 0 obj
<<
/Dests 22 0 R
>>
endobj
7 0 obj
<<
/Count 25
/First 23 0 R
/Last 23 0 R
/Type /Outlines
>>
endobj
9 0 obj
<<
/Resources 24 0 R
/Type /Page
/MediaBox [0.0 0.0 612.0 792.0]
/CropBox [0.0 0.0 612.0 792.0]
/BleedBox [0 0 612 792]
/TrimBox [0 0 612 792]
/Parent 2 0 R
/StructParents 0
/Tabs /S
/Annots [25 0 R 26 0 R 27 0 R 28 0 R 29 0 R]
/Contents 30 0 R
/Rotate 0
>>
endobj
10 0 obj
<<
/Annots [31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R 40 0 R
41 0 R 42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents [48 0 R 49 0 R 50 0 R 51 0 R 52 0 R 53 0 R 54 0 R 55 0 R]
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 56 0 R
/Rotate 0
/StructParents 248
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
11 0 obj
<<
/Annots [57 0 R 58 0 R 59 0 R 60 0 R 61 0 R 62 0 R 63 0 R 64 0 R 65 0 R 66 0 R
67 0 R 68 0 R 69 0 R 70 0 R 71 0 R 72 0 R 73 0 R 74 0 R 75 0 R 76 0 R
77 0 R 78 0 R 79 0 R 80 0 R 81 0 R 82 0 R 83 0 R 84 0 R 85 0 R 86 0 R
87 0 R 88 0 R 89 0 R 90 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 91 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 92 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
12 0 obj
<<
/Annots [93 0 R 94 0 R 95 0 R 96 0 R 97 0 R 98 0 R 99 0 R 100 0 R 101 0 R 102 0 R
103 0 R 104 0 R 105 0 R 106 0 R 107 0 R 108 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 109 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 110 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
13 0 obj
<<
/Annots [111 0 R 112 0 R 113 0 R 114 0 R 115 0 R 116 0 R 117 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 118 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 119 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
14 0 obj
<<
/Annots [120 0 R 121 0 R 122 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 123 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 124 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
15 0 obj
<<
/Annots [125 0 R 126 0 R 127 0 R 128 0 R 129 0 R 130 0 R 131 0 R 132 0 R 133 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 134 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 135 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
16 0 obj
<<
/Annots [136 0 R 137 0 R 138 0 R 139 0 R 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R 145 0 R
146 0 R 147 0 R 148 0 R 149 0 R 150 0 R 151 0 R 152 0 R 153 0 R 154 0 R 155 0 R
156 0 R 157 0 R 158 0 R 159 0 R 160 0 R 161 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 162 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 163 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
17 0 obj
<<
/Annots [164 0 R 165 0 R 166 0 R 167 0 R 168 0 R 169 0 R 170 0 R 171 0 R 172 0 R 173 0 R
174 0 R 175 0 R 176 0 R 177 0 R 178 0 R 179 0 R 180 0 R 181 0 R 182 0 R 183 0 R
184 0 R 185 0 R 186 0 R 187 0 R 188 0 R 189 0 R 190 0 R 191 0 R 192 0 R 193 0 R
194 0 R 195 0 R 196 0 R 197 0 R 198 0 R 199 0 R 200 0 R 201 0 R 202 0 R 203 0 R
204 0 R 205 0 R 206 0 R 207 0 R 208 0 R 209 0 R 210 0 R 211 0 R 212 0 R 213 0 R
214 0 R 215 0 R 216 0 R 217 0 R 218 0 R 219 0 R 220 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 221 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 222 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
18 0 obj
<<
/Annots [223 0 R 224 0 R 225 0 R 226 0 R 227 0 R 228 0 R 229 0 R 230 0 R 231 0 R 232 0 R
233 0 R 234 0 R 235 0 R 236 0 R 237 0 R 238 0 R 239 0 R 240 0 R 241 0 R 242 0 R
243 0 R 244 0 R 245 0 R 246 0 R 247 0 R 248 0 R 249 0 R 250 0 R 251 0 R 252 0 R
253 0 R 254 0 R 255 0 R 256 0 R 257 0 R 258 0 R 259 0 R 260 0 R 261 0 R 262 0 R
263 0 R 264 0 R 265 0 R 266 0 R 267 0 R 268 0 R 269 0 R 270 0 R 271 0 R 272 0 R
273 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 274 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 275 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
19 0 obj
<<
/Annots [276 0 R 277 0 R 278 0 R 279 0 R 280 0 R 281 0 R 282 0 R 283 0 R 284 0 R 285 0 R
286 0 R 287 0 R 288 0 R 289 0 R 290 0 R 291 0 R 292 0 R 293 0 R 294 0 R 295 0 R
296 0 R 297 0 R 298 0 R 299 0 R 300 0 R 301 0 R 302 0 R 303 0 R 304 0 R 305 0 R
306 0 R 307 0 R 308 0 R 309 0 R 310 0 R 311 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents 312 0 R
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 2 0 R
/Resources 313 0 R
/Rotate 0
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
20 0 obj
<<
/S /D
>>
endobj
21 0 obj
<<
/Annots [314 0 R 315 0 R 316 0 R 317 0 R 318 0 R 319 0 R 320 0 R 321 0 R 322 0 R 323 0 R
324 0 R 325 0 R 326 0 R 327 0 R 328 0 R 329 0 R 330 0 R]
/ArtBox [0.0 0.0 595.276 779.528]
/BleedBox [0.0 0.0 595.276 779.528]
/Contents [331 0 R 332 0 R 333 0 R 334 0 R 335 0 R 336 0 R 337 0 R 338 0 R]
/CropBox [0.0 0.0 595.276 779.528]
/MediaBox [0.0 0.0 595.276 779.528]
/Parent 339 0 R
/Resources <<
/ExtGState <<
/GS0 340 0 R
/GS1 341 0 R
>>
/Font <<
/T1_0 342 0 R
/T1_1 343 0 R
/T1_2 344 0 R
/T1_3 345 0 R
/T1_4 346 0 R
/T1_5 347 0 R
/T1_6 348 0 R
>>
/ProcSet [/PDF /Text]
/Properties <<
/MC0 349 0 R
/MC1 350 0 R
/MC2 351 0 R
>>
/XObject <<
/Fm0 352 0 R
>>
>>
/Rotate 0
/StructParents 248
/TrimBox [0.0 0.0 595.276 779.528]
/Type /Page
>>
endobj
22 0 obj
<<
/Kids [353 0 R 354 0 R]
>>
endobj
23 0 obj
<<
/A 355 0 R
/Count 24
/First 356 0 R
/Last 357 0 R
/Parent 7 0 R
/Title
>>
endobj
24 0 obj
<<
/Font 358 0 R
/ProcSet [/PDF /ImageB /ImageC /Text]
/XObject <<
/Im1 359 0 R
/Im2 360 0 R
>>
/ColorSpace 361 0 R
>>
endobj
25 0 obj
<<
/Type /Annot
/Subtype /Link
/Rect [50.0 433.368 338.432 445.368]
/C [0 0 0]
/Border [0 0 0]
/A 362 0 R
/H /I
/StructParent 1
>>
endobj
26 0 obj
<<
/Type /Annot
/Subtype /Link
/Rect [489.344 372.768 522.32 384.768]
/C [0 0 0]
/Border [0 0 0]
/A 363 0 R
/H /I
/StructParent 2
>>
endobj
27 0 obj
<<
/Type /Annot
/Subtype /Link
/Rect [50.0 358.368 427.448 370.368]
/C [0 0 0]
/Border [0 0 0]
/A 363 0 R
/H /I
/StructParent 3
>>
endobj
28 0 obj
<<
/Type /Annot
/Subtype /Link
/Rect [278.48 278.168 361.172 290.168]
/C [0 0 0]
/Border [0 0 0]
/A 364 0 R
/H /I
/StructParent 4
>>
endobj
29 0 obj
<<
/Type /Annot
/Subtype /Link
/Rect [50.0 243.768 115.424 255.768]
/C [0 0 0]
/Border [0 0 0]
/A 365 0 R
/H /I
/StructParent 5
>>
endobj
30 0 obj
<<
/Length 2315
/Filter /FlateDecode
>>
stream
x\K4_%,.ET+h
j%?vs{iE>><||?xY/>>1n^}ϗwݓ'7o~ѱOO^<j'\ON{It/>=|ĺy^EK"P
tO+;!7o'.zmDSi0tc:1sҐ?CvWLz*Ob籑fHCdO5uz=:5\B]{)q<&X*z\7"D4Eȴ|ff)8bq6S,2&C]ܗ[0)D` ,8`k@""ltxKy(Y[%O|el:N5;"Vyא&4x4l*SuZ JSiZP)c@xGTdoC-F^6A
0"#YυcLH9F,mFn)&K`Q@.h-gNLfOcxf's!.OEʅURLh|ex8nD'"xҝRA0+wLZCG1L#&NTh:(X(Cdd_jl1Nfcgj"AЇ:jќ D$C֜Xu̺LFuMZj:˗ħ nUuTf{uS&BtE}xkR+1˜`.$r[]``5M:p té
{sMڠmc1d:?Gdė@jFY#RLJXEݞz|4єTrjZ"jbczf\-a!H6%AW@i~Jh Oj$zP)mIbdH:en*z5JSݤ2@=f7X|Gk}":n$fz(\gV2vjhN~8Nn6cP :&gƟ6m4'-i\%ݑ8 $k=nmo#ez=xIuR"VzHRC j6eWI"4Xע
)GbI;TAGH?Ke"Ԩ;d[Qg%K# 4"u4fv[U$gj+>bi5Kd)>p9uUpHHAVOwk$Pu
1!<B4pg%uueK@q!c\sv (S_ď<ŝq[aIz-o/!,rtEuj3![]xg ڪ~" vΠI\Vyo4w"asQ;R߶nl"-&jTh6UJrE2Yb:QGͷu
&3^"[V1'P}0ݍ7JǮzI>ZDžhrr ңp`xl /7nJc̳u($-[Hb:Q,cXݨTR^8nTή)Xˣn\:iw!Gl#u=,Rڼ%vgH螂T?]Amw2\rbS]5
MER 5}%犮zI~0]-NEI
ۡ}]cg G+Ʒj %
x;l@(f7&$1NfbfrueZ^ب6e%C*$uuz]cmrks
rc "
QtbOM0oSxqlV/-~0w(^ãNV1csBd=.ep̫r|RyZz]oޭQ {șʼ
(7
]E.Q30b}O6C
Xz?x^m;kzҚ_lU@Qެ}i6cV"@"z0\v=xNL:K}
./&