Now showing items 1-4 of 4

    • Altered distribution of mucosal NK cells during HIV infection 

      Sips, Magdalena; Sciaranghella, Gaia; Diefenbach, Thomas; Dugast, Anne-Sophie; Berger, Christoph T.; Liu, Qingquan; Kwon, Douglas; Ghebremichael, Musie; Estes, Jacob D.; Carrington, Mary; Martin, Jeffrey N.; Deeks, Steven G.; Hunt, Peter W.; Alter, Galit (2013)
      The human gut mucosa is a major site of HIV infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells play an important role in control of HIV infection but the mechanism(s) ...
    • Association between CTL Precursor Frequency to HLA-C Mismatches and HLA-C Antigen Cell Surface Expression 

      Israeli, Moshe; Roelen, Dave L.; Carrington, Mary; Petersdorf, Effie Wang; Claas, Frans H. J.; Haasnoot, Geert W.; Oudshoorn, Machteld (Frontiers Media S.A., 2014)
      Previous studies showed the relevance of the cytotoxic T-cell precursor (CTLp) frequency assay for prediction of the outcome of HLA mismatched hematopoietic cell transplantation (HCT). Recently, it has been shown that HLA-C ...
    • Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control 

      Ranasinghe, Srinika; Cutler, Sam; Davis, Isaiah; Lu, Richard; Soghoian, Damien Z.; Qi, Ying; Sidney, John; Kranias, Gregory; Flanders, Michael; Lindqvist, Madelene; Kuhl, Bjorn; Alter, Galit; Deeks, Steven G.; Walker, Bruce D.; Gao, Xiaojiang; Sette, Alessandro; Carrington, Mary; Streeck, Hendrik (2013)
      The contribution of HLA class II-restricted CD4+ T cell responses to HIV immune control is poorly defined. Here, we delineated novel peptide-DRB1 restrictions in functional assays and analyzed the host genetic effects of ...
    • IFNL3 (IL28B) favorable genotype escapes hepatitis C virus-induced microRNAs and mRNA decay 

      McFarland, Adelle P.; Horner, Stacy M.; Jarret, Abigail; Joslyn, Rochelle C.; Bindewald, Eckart; Shapiro, Bruce A.; Delker, Don A.; Hagedorn, Curt; Carrington, Mary; Gale, Michael; Savan, Ram (2014)
      The IFNL3 (IL28B) gene has received immense attention in the hepatitis C virus (HCV) field as multiple independent genome-wide association studies identified a strong association between polymorphisms near the IFNL3 gene ...