Browsing by Author "Joyce, Eric F."
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Germline Progenitors Escape the Widespread Phenomenon of Homolog Pairing during Drosophila Development
Joyce, Eric F.; Apostolopoulos, Nicholas; Beliveau, Brian J.; Wu, C. -ting (Public Library of Science, 2013)Homolog pairing, which plays a critical role in meiosis, poses a potential risk if it occurs in inappropriate tissues or between nonallelic sites, as it can lead to changes in gene expression, chromosome entanglements, and ... -
The Histone H4 Lysine 20 Monomethyl Mark, Set by PR-Set7 and Stabilized by L(3)mbt, Is Necessary for Proper Interphase Chromatin Organization
Sakaguchi, Ayako; Joyce, Eric; Aoki, Tsutomu; Schedl, Paul; Steward, Ruth (Public Library of Science, 2012)Drosophila PR-Set7 or SET8 is a histone methyltransferase that specifically monomethylates histone H4 lysine 20 (H4K20). L(3)MBT has been identified as a reader of methylated H4K20. It contains several conserved domains ... -
Identification of Genes That Promote or Antagonize Somatic Homolog Pairing Using a High-Throughput FISH–Based Screen
Joyce, Eric; Williams, Benjamin R.; Xie, Tiao; Wu, C.-ting (Public Library of Science, 2012)The pairing of homologous chromosomes is a fundamental feature of the meiotic cell. In addition, a number of species exhibit homolog pairing in nonmeiotic, somatic cells as well, with evidence for its impact on both gene ... -
Oligopaints: highly efficient, bioinformatically designed probes for fluorescence in situ hybridization
Beliveau, Brian Joseph; Joyce, Eric; Apostolopoulosa, Nicholas; Yilmaza, Feyza; Fonseka, Chamith Y; McCole, Ruth Brann; Chang, Yiming; Li, Jin Billy; Senaratne, Niroshi Niroshini; Williams, Benjamin R; Rouillard, Jean-Marie; Wu, Chao-Ting (BioMed Central, 2013) -
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes
Beliveau, Brian J.; Boettiger, Alistair N.; Avendaño, Maier S.; Jungmann, Ralf; McCole, Ruth B.; Joyce, Eric F.; Kim-Kiselak, Caroline; Bantignies, Frédéric; Fonseka, Chamith Y.; Erceg, Jelena; Hannan, Mohammed A.; Hoang, Hien G.; Colognori, David; Lee, Jeannie T.; Shih, William M.; Yin, Peng; Zhuang, Xiaowei; Wu, Chao-ting (Nature Pub. Group, 2015)Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two advances in FISH-based imaging. We first describe the in situ visualization ...