Browsing by Author "Coughlin, Margaret"

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    • The Atg1-Tor Pathway Regulates Yolk Catabolism in Drosophila Embryos 

      Kuhn, Hallie; Sopko, Richelle; Coughlin, Margaret; Perrimon, Norbert; Mitchison, Timothy (The Company of Biologists, 2015-11-15)
      Yolk provides an important source of nutrients during the early development of oviparous organisms. It is composed mainly of vitellogenin proteins packed into membrane-bound compartments called yolk platelets. Catabolism ...

    • Functional Analysis of VopF Activity Required for Colonization in Vibrio cholerae 

      Tam, Vincent C.; Suzuki, Masato; Coughlin, Margaret; Saslowsky, David; Biswas, Kuntal; Lencer, Wayne Isaac; Faruque, Shah M.; Mekalanos, John J. (American Society of Microbiology, 2010)
      Vibrio cholerae, a Gram-negative facultative pathogen, is the etiologic agent for the diarrheal disease cholera. We previously characterized a clinical isolate, AM-19226, that translocates a type III secretion system (T3SS) ...