Browsing by Author "Sonntag, Kai-Christian"

Now showing items 1-4 of 4

    • Fast and Efficient Neural Conversion of Human Hematopoietic Cells 

      Castaño, Julio; Menendez, Pablo; Bruzos-Cidon, Cristina; Straccia, Marco; Sousa, Amaia; Zabaleta, Lorea; Vazquez, Nerea; Zubiarrain, Amaia; Sonntag, Kai-Christian; Ugedo, Luisa; Carvajal-Vergara, Xonia; Canals, Josep Maria; Torrecilla, Maria; Sanchez-Pernaute, Rosario; Giorgetti, Alessandra (Elsevier, 2014)
      Summary Neurons obtained directly from human somatic cells hold great promise for disease modeling and drug screening. Available protocols rely on overexpression of transcription factors using integrative vectors and are ...

    • Implementations of Translational Medicine 

      Sonntag, Kai-Christian (BioMed Central, 2005)
      New developments in science are rapidly influencing and shaping basic and clinical research and medicine. This has led to the emergence of multiple opportunities and challenges on many levels in the bio-medical and other ...

    • Molecular Profiles of Parvalbumin-Immunoreactive Neurons in the Superior Temporal Cortex in Schizophrenia 

      Pietersen, Charmaine Y.; Mauney, Sarah A.; Kim, Susie S.; Passeri, Eleonora; Lim, Maribel P.; Rooney, Robert J.; Goldstein, Jill M.; Petreyshen, Tracey L.; Seidman, Larry Joel; Shenton, Martha Elizabeth; McCarley, Robert William; Sonntag, Kai-Christian; Woo, Tsung-Ung Wilson (Informa Healthcare, 2014)
      Dysregulation of pyramidal cell network function by the soma- and axon-targeting inhibitory neurons that contain the calcium-binding protein parvalbumin (PV) represents a core pathophysiological feature of schizophrenia. ...

    • Proteasome Activator Enhances Survival of Huntington's Disease Neuronal Model Cells 

      Seo, Hyemyung; Sonntag, Kai-Christian; Kim, Woori; Cattaneo, Elena; Isacson, Ole Stefan (Public Library of Science, 2007)
      In patients with Huntington's disease (HD), the proteolytic activity of the ubiquitin proteasome system (UPS) is reduced in the brain and other tissues. The pathological hallmark of HD is the intraneuronal nuclear protein ...