Now showing items 1-9 of 9

    • A 3T MR Imaging Investigation of the Topography of Whole Spinal Cord Atrophy in Multiple Sclerosis 

      Klein, Joshua Peter; Arora, A.; Neema, M; Healy, Brian Curran; Tauhid, Shahamat Syed; Goldberg-Zimring, D.; Chavarro-Nieto, C.; Stankiewicz, James; Cohen, Adam Brian; Buckle, G. J.; Houtchens, Maria K.; Ceccarelli, A.; Dell, E.; Guttmann, Charles R.G.; Alsop, David C.; Hackney, David Brian; Bakshi, Rohit (American Society of Neuroradiology (ASNR), 2011)
      Background and Purpose: Spinal cord atrophy is a common feature of MS. However, it is unknown which cord levels are most susceptible to atrophy. We performed whole cord imaging to identify the levels most susceptible to ...
    • Brain MRI Lesion Load at 1.5T and 3T versus Clinical Status in Multiple Sclerosis 

      Stankiewicz, James; Glanz, Bonnie; Healy, Brian Curran; Arora, Ashish; Neema, Mohit; Benedict, Ralph H.B.; Guss, Zachary D.; Tauhid, Shahamat Syed; Buckle, Guy J.; Houtchens, Maria K.; Khoury, Samia Joseph; Weiner, Howard Lee; Guttmann, Charles R.G.; Bakshi, Rohit (Wiley-Blackwell, 2011)
      Background/Purpose: To assess correlation between brain lesions and clinical status with 1.5T and 3T magnetic resonance imaging (MRI). Methods: Brain MRI fluid-attenuated inversion-recovery (FLAIR) sequences were performed ...
    • An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2 

      Bakshi, Rohit; Neema, Mohit; Tauhid, Shahamat; Healy, Brian C.; Glanz, Bonnie I.; Kim, Gloria; Miller, Jennifer; Berkowitz, Julia L.; Bove, Riley; Houtchens, Maria K.; Severson, Christopher; Stankiewicz, James M.; Stazzone, Lynn; Chitnis, Tanuja; Guttmann, Charles R.G.; Weiner, Howard L.; Ceccarelli, Antonia (Lippincott Williams & Wilkins, 2014)
      The objective of this study was to test a new version of the Magnetic Resonance Disease Severity Scale (MRDSS2), incorporating cerebral gray matter (GM) and spinal cord involvement from 3 T MRI, in modeling the relationship ...
    • The Impact of Lesion In-Painting and Registration Methods on Voxel-Based Morphometry in Detecting Regional Cerebral Gray Matter Atrophy in Multiple Sclerosis 

      Ceccarelli, A.; Jackson, J. S.; Tauhid, S.; Arora, A; Gorky, J.; Dell, E.; Bakshi, A.; Chitnis, Tanuja; Khoury, Samia Joseph; Weiner, Howard Lee; Guttmann, Charles R.G.; Bakshi, Rohit; Neema, Mohit (American Society of Neuroradiology (ASNR), 2012)
      Background and Purpose: VBM has been widely used to study GM atrophy in MS. MS lesions lead to segmentation and registration errors that may affect the reliability of VBM results. Improved segmentation and registration ...
    • Microstructural Changes in the Striatum and Their Impact on Motor and Neuropsychological Performance in Patients with Multiple Sclerosis 

      Cavallari, Michele; Ceccarelli, Antonia; Wang, Guang-Yi; Moscufo, Nicola; Hannoun, Salem; Matulis, Christina R.; Jackson, Jonathan S.; Glanz, Bonnie I.; Bakshi, Rohit; Neema, Mohit; Guttmann, Charles R. G. (Public Library of Science, 2014)
      Grey matter (GM) damage is a clinically relevant feature of multiple sclerosis (MS) that has been previously assessed with diffusion tensor imaging (DTI). Fractional anisotropy (FA) of the basal ganglia and thalamus might ...
    • MRI phenotypes based on cerebral lesions and atrophy in patients with multiple sclerosis 

      Tauhid, Shahamat Syed; Neema, Mohit; Healy, Brian Curran; Weiner, Howard Lee; Bakshi, Rohit (Elsevier BV, 2014)
      Background: While disease categories (i.e. clinical phenotypes) of multiple sclerosis (MS) are established, there remains MRI heterogeneity among patients within those definitions. MRI-defined lesions and atrophy show only ...
    • Normal Findings on Brain Fluid-Attenuated Inversion Recovery MR Images at 3T 

      Neema, M; Guss, Z.D.; Stankiewicz, James; Arora, A; Healy, Brian Curran; Bakshi, Rohit (American Society of Neuroradiology (ASNR), 2009)
      Background and Purpose: Fluid attenuated inversion recovery (FLAIR) MR imaging of the brain has become a routine tool for assessing lesions in patients with suspected neurologic disorders. There is growing interest in 3T ...
    • Quantification of Global Cerebral Atrophy in Multiple Sclerosis from 3T MRI Using SPM: The Role of Misclassification Errors 

      Dell’Oglio, Elisa; Ceccarelli, Antonia; Glanz, Bonnie I; Healy, Brian C; Tauhid, Shahamat; Arora, Ashish; Saravanan, Nikila; Bruha, Matthew J; Vartanian, Alexander V; Dupuy, Sheena L; Benedict, Ralph HB; Bakshi, Rohit; Neema, Mohit (BlackWell Publishing Ltd, 2014)
      Purpose We tested the validity of a freely available segmentation pipeline to measure compartmental brain volumes from 3T MRI in patients with multiple sclerosis (MS). Our primary focus was methodological to explore the ...
    • Whole Brain Volume Measured from 1.5T versus 3T MRI in Healthy Subjects and Patients with Multiple Sclerosis 

      Chu, Renxin; Tauhid, Shahamat Syed; Glanz, Bonnie; Healy, Brian Curran; Kim, Gloria; Oommen, Vinit V.; Khalid, Fariha; Neema, Mohit; Bakshi, Rohit (Wiley-Blackwell, 2015)
      Background: Whole brain atrophy is a putative outcome measure in monitoring relapsing-remitting multiple sclerosis (RRMS). With the ongoing MRI transformation from 1.5T to 3T, there is an unmet need to calibrate this change. ...