Browsing by Author "Merbl, Yifat Haya"
Now showing items 1-3 of 3
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Microarray Discovery of New OGT Substrates: The Medulloblastoma Oncogene OTX2 Is O-GlcNAcylated
Ortiz-Meoz, Rodrigo F.; Merbl, Yifat; Kirschner, Marc W.; Walker, Suzanne (American Chemical Society, 2014)O-GlcNAc transferase (OGT) is a serine/threonine glycosyltransferase that is essential for development and continues to be critically important throughout life. Understanding OGT’s complex biology requires identifying its ... -
Network Theory Analysis of Antibody-Antigen Reactivity Data: The Immune Trees at Birth and Adulthood
Madi, Asaf; Kenett, Dror Y.; Bransburg-Zabary, Sharron; Merbl, Yifat Haya; Quintana, Francisco Javier; Tauber, Alfred I.; Cohen, Irun R.; Ben-Jacob, Eshel (Public Library of Science, 2011)Motivation: New antigen microarray technology enables parallel recording of antibody reactivities with hundreds of antigens. Such data affords system level analysis of the immune system’s organization using methods and ... -
A Systems Immunology Approach to the Host-Tumor Interaction: Large-Scale Patterns of Natural Autoantibodies Distinguish Healthy and Tumor-Bearing Mice
Merbl, Yifat Haya; Itzchak, Royi; Vider-Shalit, Tal; Louzoun, Yoram; Quintana, Francisco Javier; Vadai, Ezra; Eisenbach, Lea; Cohen, Irun R. (Public Library of Science, 2009)Traditionally, immunology has considered a meaningful antibody response to be marked by large amounts of high-affinity antibodies reactive with the specific inciting antigen; the detection of small amounts of low-affinity ...