Browsing by Author "Fregni, Felipe"
Now showing items 1-20 of 44
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Association of anxiety with intracortical inhibition and descending pain modulation in chronic myofascial pain syndrome
Vidor, Liliane Pinto; Torres, Iraci LS; Medeiros, Liciane Fernandes; Dussán-Sarria, Jairo Alberto; Dall’Agnol, Letizzia; Deitos, Alicia; Brietzke, Aline; Laste, Gabriela; Rozisky, Joanna R; Fregni, Felipe; Caumo, Wolnei (BioMed Central, 2014)Background: This study aimed to answer three questions related to chronic myofascial pain syndrome (MPS): 1) Is the motor cortex excitability, as assessed by transcranial magnetic stimulation parameters (TMS), related to ... -
Attentional modulation of emotional stimulus processing: An fMRI study using emotional expectancy
Bermpohl, Felix; Pascual-Leone, Alvaro; Amedi, Amir; Merabet, Lotfi B; Fregni, Felipe; Gaab, Nadine; Alsop, David C.; Schlaug, Gottfried; Northoff, Georg (Wiley-Blackwell, 2006)We used emotional expectancy to study attentional modulation in the processing of emotional stimuli. During functional magnetic resonance imaging (fMRI), volunteers saw emotional and neutral expectancy cues signaling the ... -
Changes in Clinical Trials Methodology Over Time: A Systematic Review of Six Decades of Research in Psychopharmacology
Brunoni, André R.; Tadini, Laura; Fregni, Felipe (Public Library of Science, 2010)Background: There have been many changes in clinical trials methodology since the introduction of lithium and the beginning of the modern era of psychopharmacology in 1949. The nature and importance of these changes have ... -
Chronic Pain Following Physical and Emotional Trauma: The Station Nightclub Fire
Egyhazi, Rachel; Fregni, Felipe; Bravo, Gabriela L.; Trinh, Nhi-Ha T.; Ryan, Colleen M.; Schneider, Jeffrey C. (Frontiers Media S.A., 2014)Objective: The purpose of this study was to evaluate factors associated with chronic pain in survivors of a large fire, including those with and without burn injury. Methods: This study employed a survey-based cross-sectional ... -
Clinical research in pediatric organ transplantation
Azeka, Estela; Saavedra, Laura Castillo; Fregni, Felipe (Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 2014)Solid organ transplantation has greatly improved survival in children with end-stage disease, becoming one of the main treatment options in this population. Nonetheless, there are significant challenges associated with ... -
Clinical utility of brain stimulation modalities following traumatic brain injury: current evidence
Li, Shasha; Zaninotto, Ana Luiza; Neville, Iuri Santana; Paiva, Wellingson Silva; Nunn, Danuza; Fregni, Felipe (Dove Medical Press, 2015)Traumatic brain injury (TBI) remains the main cause of disability and a major public health problem worldwide. This review focuses on the neurophysiology of TBI, and the rationale and current state of evidence of clinical ... -
Combining Dopaminergic Facilitation with Robot-Assisted Upper Limb Therapy in Stroke Survivors: A Focused Review
Tran, Duc A.; Pajaro-Blazquez, Marta; Daneault, Jean-Francois; Gallegos, Jaime G.; Pons, Jose; Fregni, Felipe; Bonato, Paolo; Zafonte, Ross (Lippincott Williams & Wilkins, 2016)ABSTRACT Despite aggressive conventional therapy, lasting hemiplegia persists in a large percentage of stroke survivors. The aim of this article is to critically review the rationale behind targeting multiple sites along ... -
Degos disease – malignant atrophic papulosis or cutaneointestinal lethal syndrome: rarity of the disease
Pirolla, Eduardo; Fregni, Felipe; Miura, Irene K; Misiara, Antonio Carlos; Almeida, Fernando; Zanoni, Esdras (Dove Medical Press, 2015)Background: Degos disease is a very rare syndrome with a rare type of multisystem vasculopathy of unknown cause that affects the skin, gastrointestinal tract, and central nervous system. Other organs such as the kidneys, ... -
Descending Control of Nociceptive Processing in Knee Osteoarthritis Is Associated With Intracortical Disinhibition: An Exploratory Study
Tarragó, Maria da Graca L.; Deitos, Alícia; Brietzke, Aline Patrícia; Vercelino, Rafael; Torres, Iraci L. S.; Fregni, Felipe; Caumo, Wolnei (Wolters Kluwer Health, 2016)Abstract Based on the hypothesis that an imbalance in excitatory and inhibitory input is a central mechanism of knee osteoarthritis chronic pain (KOACP), this exploratory study had the following aims: to compare whether ... -
Dissociation of Motor Task-Induced Cortical Excitability and Pain Perception Changes in Healthy Volunteers
Volz, Magdalena S.; Mendonca, Mariana; Pinheiro, Fernando S.; Cui, Huashun; Santana, Marcus; Fregni, Felipe (Public Library of Science, 2012)Background: There is evidence that interventions aiming at modulation of the motor cortex activity lead to pain reduction. In order to understand further the role of the motor cortex on pain modulation, we aimed to compare ... -
Effect of a single session of transcranial direct-current stimulation on balance and spatiotemporal gait variables in children with cerebral palsy: A randomized sham-controlled study
Grecco, Luanda A. C.; Duarte, Natália A. C.; Zanon, Nelci; Galli, Manuela; Fregni, Felipe; Oliveira, Claudia S. (Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia, 2014)Background: Transcranial direct-current stimulation (tDCS) has been widely studied with the aim of enhancing local synaptic efficacy and modulating the electrical activity of the cortex in patients with neurological ... -
Effect of transcranial direct current stimulation combined with gait and mobility training on functionality in children with cerebral palsy: study protocol for a double-blind randomized controlled clinical trial
Grecco, Luanda André Collange; Duarte, Natália de Almeida Carvalho; de Mendonça, Mariana Emerenciano; Pasini, Hugo; Lima, Vânia Lúcia Costa de Carvalho; Franco, Renata Calhes; de Oliveira, Luis Vicente Franco; de Carvalho, Paulo de Tarso Camilo; Corrêa, João Carlos Ferrari; Collange, Nelci Zanon; Sampaio, Luciana Maria Malosá; Galli, Manuela; Fregni, Felipe; Oliveira, Claudia Santos (BioMed Central, 2013)Background: The project proposes three innovative intervention techniques (treadmill training, mobility training with virtual reality and transcranial direct current stimulation that can be safely administered to children ... -
Effect of Transcranial Direct-Current Stimulation Combined with Treadmill Training on Balance and Functional Performance in Children with Cerebral Palsy: A Double-Blind Randomized Controlled Trial
Duarte, Natália de Almeida Carvalho; Grecco, Luanda André Collange; Galli, Manuela; Fregni, Felipe; Oliveira, Cláudia Santos (Public Library of Science, 2014)Background: Cerebral palsy refers to permanent, mutable motor development disorders stemming from a primary brain lesion, causing secondary musculoskeletal problems and limitations in activities of daily living. The aim ... -
Effects of Sensory Behavioral Tasks on Pain Threshold and Cortical Excitability
Volz, Magdalena Sarah; Suarez-Contreras, Vanessa; Mendonca, Mariana E.; Pinheiro, Fernando Santos; Merabet, Lotfi B.; Fregni, Felipe (Public Library of Science, 2013)Background/objective: Transcutaneous electrical stimulation has been proven to modulate nervous system activity, leading to changes in pain perception, via the peripheral sensory system, in a bottom up approach. We tested ... -
Electroacupuncture analgesia is associated with increased serum brain-derived neurotrophic factor in chronic tension-type headache: a randomized, sham controlled, crossover trial
Chassot, Mônica; Dussan-Sarria, Jairo Alberto; Sehn, Francislea Cristina; Deitos, Alícia; de Souza, Andressa; Vercelino, Rafael; Torres, Iraci LS; Fregni, Felipe; Caumo, Wolnei (BioMed Central, 2015)Background: Chronic tension-type headache (CTTH) is characterized by almost daily headaches and central sensitization, for which electroacupuncture (EA) might be effective. The central nervous system (CNS) plasticity can ... -
Electrode Positioning and Montage in Transcranial Direct Current Stimulation
DaSilva, Alexandre F.; Volz, Magdalena Sarah; Bikson, Marom; Fregni, Felipe (MyJove Corporation, 2011)Transcranial direct current stimulation (tDCS) is a technique that has been intensively investigated in the past decade as this method offers a non-invasive and safe alternative to change cortical excitability. The effects ... -
A Framework for Understanding the Relationship between Descending Pain Modulation, Motor Corticospinal, and Neuroplasticity Regulation Systems in Chronic Myofascial Pain
Botelho, Leonardo M.; Morales-Quezada, Leon; Rozisky, Joanna R.; Brietzke, Aline P.; Torres, Iraci L. S.; Deitos, Alicia; Fregni, Felipe; Caumo, Wolnei (Frontiers Media S.A., 2016)Myofascial pain syndrome (MPS) is a leading cause of chronic musculoskeletal pain. However, its neurobiological mechanisms are not entirely elucidated. Given the complex interaction between the networks involved in pain ... -
Head-to-Head Comparison of Transcranial Random Noise Stimulation, Transcranial AC Stimulation, and Transcranial DC Stimulation for Tinnitus
Vanneste, Sven; Fregni, Felipe; De Ridder, Dirk (Frontiers Media S.A., 2013)Tinnitus is the perception of a sound in the absence of an external sound stimulus. This phantom sound has been related to plastic changes and hyperactivity in the auditory cortex. Different neuromodulation techniques such ... -
Improving Cycling Performance: Transcranial Direct Current Stimulation Increases Time to Exhaustion in Cycling
Vitor-Costa, Marcelo; Okuno, Nilo Massaru; Bortolotti, Henrique; Bertollo, Maurizio; Boggio, Paulo Sergio; Fregni, Felipe; Altimari, Leandro Ricardo (Public Library of Science, 2015)The central nervous system seems to have an important role in fatigue and exercise tolerance. Novel noninvasive techniques of neuromodulation can provide insights on the relationship between brain function and exercise ... -
Je pense donc je fais: transcranial direct current stimulation modulates brain oscillations associated with motor imagery and movement observation
Lapenta, Olivia M.; Minati, Ludovico; Fregni, Felipe; Boggio, Paulo S. (Frontiers Media S.A., 2013)Motor system neural networks are activated during movement imagery, observation and execution, with a neural signature characterized by suppression of the Mu rhythm. In order to investigate the origin of this neurophysiological ...