Now showing items 1-14 of 14

    • Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects 

      Hui, Kathleen K.S.; Marina, Ovidiu; Claunch, Joshua D.; Nixon, Erika E.; Fang, Jiliang; Liu, Jing; Li, Ming; Napadow, Vitaly J.; Vangel, Mark G.; Makris, Nikos; Chan, Suk Tak; Kwong, Kenneth Kin Man; Rosen, Bruce (Elsevier BV, 2009)
      Previous work has shown that acupuncture stimulation evokes deactivation of a limbic-paralimbic-neocortical network (LPNN) as well as activation of somatosensory brain regions. This study explores the activity and functional ...
    • Brain encoding of acupuncture sensation — Coupling on-line rating with fMRI 

      Napadow, Vitaly J.; Dhond, Rupali P.; Kim, Jieun; LaCount, Lauren; Vangel, Mark G.; Harris, Richard E; Kettner, Norman; Park, Kyungmo (Elsevier BV, 2009)
      Acupuncture-induced sensations have historically been associated with clinical efficacy. These sensations are atypical, arising from sub-dermal receptors, and their neural encoding is not well known. In this fMRI study, ...
    • Brain white matter microstructure is associated with susceptibility to motion-induced nausea 

      Napadow, Vitaly J.; Sheehan, J.; Kim, Jieun; Dassatti, Allison; Thurler, Andrea H.; Surjanhata, Brian; Vangel, Mark G.; Makris, Nikolaos; Schaechter, Judith Diane; Kuo, Braden (Wiley, 2013)
      Nausea is associated with significant morbidity, and there is a wide range in the propensity of individuals to experience nausea. The neural basis of this heterogeneity in nausea susceptibility is poorly understood. Our ...
    • Change in Brainstem Gray Matter Concentration Following a Mindfulness-Based Intervention is Correlated with Improvement in Psychological Well-Being 

      Singleton, Omar; Hölzel, Britta K.; Vangel, Mark; Brach, Narayan; Carmody, James; Lazar, Sara W. (Frontiers Media S.A., 2014)
      Individuals can improve their levels of psychological well-being (PWB) through utilization of psychological interventions, including the practice of mindfulness meditation, which is defined as the non-judgmental awareness ...
    • Default mode network connectivity encodes clinical pain: An arterial spin labeling study 

      Loggia, Marco Luciano; Kim, Jieun; Gollub, Randy Lyanne; Vangel, Mark G.; Kirsch, Irving; Kong, Jian; Wasan, Ajay D.; Napadow, Vitaly J. (Ovid Technologies (Wolters Kluwer Health), 2013)
      Neuroimaging studies have suggested the presence of alterations in the anatomo-functional properties of the brain of patients with chronic pain. However, investigation of the brain circuitry supporting the perception of ...
    • Differences in cortical response to acupressure and electroacupuncture stimuli 

      Witzel, Thomas; Napadow, Vitaly J.; Kettner, Norman W; Vangel, Mark G.; Hamalainen, Matti S.; Dhond, Rupali P (Springer Nature, 2011)
      Background FMRI studies focus on sub-cortical effects of acupuncture stimuli. The purpose of this study was to assess changes in primary somatosensory (S1) activity over the course of different types of acupuncture ...
    • Disentangling linear and nonlinear brain responses to evoked deep tissue pain 

      Loggia, Marco Luciano; Edwards, Robert R; Kim, Jieun; Vangel, Mark G.; Wasan, Ajay D.; Gollub, Randy Lyanne; Harris, Richard E.; Park, Kyungmo; Napadow, Vitaly J. (Ovid Technologies (Wolters Kluwer Health), 2012)
      Pain stimuli evoke widespread responses in the brain. However, our understanding of the physiological significance underlying heterogeneous response within different pain-activated and -deactivated regions is still limited. ...
    • Dissociable Genetic Contributions to Error Processing: A Multimodal Neuroimaging Study 

      Agam, Yigal; Vangel, Mark; Roffman, Joshua L.; Gallagher, Patience J.; Chaponis, Jonathan; Haddad, Stephen; Goff, Donald C.; Greenberg, Jennifer L.; Wilhelm, Sabine; Smoller, Jordan W.; Manoach, Dara S. (Public Library of Science, 2014)
      Background: Neuroimaging studies reliably identify two markers of error commission: the error-related negativity (ERN), an event-related potential, and functional MRI activation of the dorsal anterior cingulate cortex ...
    • Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks 

      Kim, Hyungjun; Kim, Jieun; Loggia, Marco L.; Cahalan, Christine; Garcia, Ronald G.; Vangel, Mark G.; Wasan, Ajay D.; Edwards, Robert R.; Napadow, Vitaly (Elsevier, 2015)
      Altered brain morphometry has been widely acknowledged in chronic pain, and recent studies have implicated altered network dynamics, as opposed to properties of individual brain regions, in supporting persistent pain. ...
    • Hypothalamus and amygdala response to acupuncture stimuli in carpal tunnel syndrome 

      Napadow, Vitaly J.; Kettner, N.; Liu, J.; Li, M.; Kwong, Kenneth Kin Man; Vangel, Mark G.; Makris, Nikolaos; Audette, Joseph F.; Hui, K. K.S. (Ovid Technologies (Wolters Kluwer Health), 2007)
      Brain processing of acupuncture stimuli in chronic neuropathic pain patients may underlie its beneficial effects. We used fMRI to evaluate verum and sham acupuncture stimulation at acupoint LI-4 in Carpal Tunnel Syndrome ...
    • A Longitudinal Study of the Reliability of Acupuncture Deqi Sensations in Knee Osteoarthritis 

      Spaeth, Rosa B.; Camhi, Stephanie; Hashmi, Javeria A.; Vangel, Mark; Wasan, Ajay D.; Edwards, Robert R.; Gollub, Randy L.; Kong, Jian (Hindawi Publishing Corporation, 2013)
      Deqi is one of the core concepts in acupuncture theory and encompasses a range of sensations. In this study, we used the MGH Acupuncture Sensation Scale (MASS) to measure and assess the reliability of the sensations evoked ...
    • The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients 

      Chen, Xiaoyan; Spaeth, Rosa B.; Freeman, Sonya G.; Scarborough, Donna Moxley; Hashmi, Javeria A.; Wey, Hsiao-Ying; Egorova, Natalia; Vangel, Mark; Mao, Jianren; Wasan, Ajay D.; Edwards, Robert R.; Gollub, Randy L.; Kong, Jian (BioMed Central, 2015)
      Recent advances in brain imaging have contributed to our understanding of the neural activity associated with acupuncture treatment. In this study, we investigated functional connectivity across longitudinal acupuncture ...
    • Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients12 

      Jafari-Khouzani, Kourosh; Emblem, Kyrre E.; Kalpathy-Cramer, Jayashree; Bjørnerud, Atle; Vangel, Mark G.; Gerstner, Elizabeth R.; Schmainda, Kathleen M.; Paynabar, Kamran; Wu, Ona; Wen, Patrick Y.; Batchelor, Tracy; Rosen, Bruce; Stufflebeam, Steven M. (Neoplasia Press, 2015)
      OBJECTIVES This study evaluates the repeatability of brain perfusion using dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) with a variety of post-processing methods. METHODS Thirty-two patients with ...
    • Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives 

      Manoach, Dara S.; Demanuele, Charmaine; Wamsley, Erin J.; Vangel, Mark; Montrose, Debra M.; Miewald, Jean; Kupfer, David; Buysse, Daniel; Stickgold, Robert; Keshavan, Matcheri S. (Frontiers Media S.A., 2014)
      Introduction: Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether ...