Browsing by Author "Martinez, Natalia J"
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Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation
Chang, Hao-Ming; Martinez, Natalia J; Thornton, James Edward; Gregory, Richard Ian (Nature Publishing Group, 2012)Pluripotent embryonic stem cells (ESCs) have a shortened cell cycle that enables their rapid proliferation. The ESC-specific miR-290 and miR-302 microRNA families promote proliferation whereas let-7 microRNAs inhibit ...