Browsing by Author "Savadjiev, Peter"
Now showing items 1-7 of 7
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Beyond Crossing Fibers: Bootstrap Probabilistic Tractography Using Complex Subvoxel Fiber Geometries
Campbell, Jennifer S. W.; MomayyezSiahkal, Parya; Savadjiev, Peter; Leppert, Ilana R.; Siddiqi, Kaleem; Pike, G. Bruce (Frontiers Media S.A., 2014)Diffusion magnetic resonance imaging fiber tractography is a powerful tool for investigating human white matter connectivity in vivo. However, it is prone to false positive and false negative results, making interpretation ... -
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
Whitford, Thomas; Savadjiev, Peter; Kubicki, Marek R.; O, Lauren J.; Terry, Douglas P.; Bouix, Sylvain; Westin, Carl-Fredrik; Schneiderman, Jason S.; Bobrow, Laurel; Rausch, Andrew C.; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; Pantelis, Christos; Wood, Stephen J.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2011)Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ... -
A Geometry-Based Particle Filtering Approach to White Matter Tractography
Savadjiev, Peter; Rathi, Yogesh; Malcolm, James G.; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (Springer Science + Business Media, 2010)We introduce a fibre tractography framework based on a particle filter which estimates a local geometrical model of the underlying white matter tract, formulated as a `streamline flow' using generalized helicoids. The ... -
Gray matter alterations in early aging: A diffusion magnetic resonance imaging study
Rathi, Yogesh; Pasternak, Ofer; Savadjiev, Peter; Michailovich, O.; Bouix, Sylvain; Kubicki, Marek R.; Westin, Carl-Fredrik; Makris, Nikolaos; Shenton, Martha Elizabeth (Wiley-Blackwell, 2013)Many studies have observed altered neurofunctional and structural organization in the aging brain. These observations from functional neuroimaging studies show a shift in brain activity from the posterior to the anterior ... -
Hockey Concussion Education Project, Part 3. White matter microstructure in ice hockey players with a history of concussion: a diffusion tensor imaging study
Sasaki, Takeshi; Pasternak, Ofer; Mayinger, Michael; Muehlmann, Marc; Savadjiev, Peter; Bouix, Sylvain; Kubicki, Marek R.; Fredman, Eli; Dahlben, Brian; Helmer, Karl G.; Johnson, Andrew M.; Holmes, Jeffrey D.; Forwell, Lorie A.; Skopelja, Elaine N.; Shenton, Martha Elizabeth; Echlin, Paul S.; Koerte, Inga Katharina (Journal of Neurosurgery Publishing Group (JNSPG), 2014)Object—The aim of this study was to examine the brain’s white matter microstructure using magnetic resonance diffusion tensor imaging (DTI) in ice hockey players with a history of clinically symptomatic concussion compared ... -
Local white matter geometry from diffusion tensor gradients
Savadjiev, Peter; Kindlmann, Gordon L.; Bouix, Sylvain; Shenton, Martha Elizabeth; Westin, Carl-Fredrik (Elsevier BV, 2010)We introduce a mathematical framework for computing geometrical properties of white matter fibres directly from diffusion tensor fields. The key idea is to isolate the portion of the gradient of the tensor field corresponding ... -
Localized abnormalities in the cingulum bundle in patients with schizophrenia: A Diffusion Tensor tractography study
Whitford, Thomas J.; Lee, Sun Woo; Oh, Jungsu S.; de Luis-Garcia, Rodrigo; Savadjiev, Peter; Alvarado, Jorge L.; Westin, Carl-Fredrik; Niznikiewicz, Margaret; Nestor, Paul G.; McCarley, Robert W.; Kubicki, Marek; Shenton, Martha E. (Elsevier, 2014)The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in the etiology of schizophrenia. There is growing evidence to suggest that the CB is actually comprised of a ...