Browsing by Author "Cole, Leandra Samantha"

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    • MUC1 Inhibition Leads to Decrease in PD-L1 Levels via Up-Regulation of miRNAs 

      Pyzer, Athalia Rachel; Stroopinsky, Dina; Rosenblatt, Jacalyn Mara; Anastasiadou, Eleni; Rajabi, Hasan Nabeel; Washington, Abigail; Tagde, Ashujit; Chu, Jen-Hwa; Coll, Maxwell; Jiao, AL; Tsai, LT; Tenen, DE; Cole, Leandra Samantha; Palmer, Kristen; Ephraim, A; Leaf, Rebecca Karp; Nahas, Myrna Rita; Apel, Arie; Bar-Natan, M; Jain, Salvia; McMasters, Malgorzata; Mendez, Lourdes Maria; Arnason, Jon E; Raby, Benjamin Alexander; Slack, Frank; Kufe, Donald William; Avigan, David E. (Springer Nature, 2017)
      The PD-L1/PD-1 pathway is a critical component of the immunosuppressive tumor microenvironment in acute myeloid leukemia (AML), but little is known about its regulation. We investigated the role of the MUC1 oncoprotein in ...