Browsing by Author "Jaffer, Farouc"
Now showing items 1-5 of 5
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Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study
Stein-Merlob, Ashley F.; Kessinger, Chase W.; Erdem, S. Sibel; Zelada, Henry; Hilderbrand, Scott A.; Lin, Charles P.; Tearney, Guillermo J.; Jaff, Michael R.; Reed, Guy L.; Henke, Peter K.; McCarthy, Jason R.; Jaffer, Farouc A. (Ivyspring International Publisher, 2015)Fibrinolytic therapy of venous thromboembolism (VTE) is increasingly utilized, yet limited knowledge is available regarding in vivo mechanisms that govern fibrinolytic efficacy. In particular, it is unknown how age-dependent ... -
Development and Validation of a Scoring System for Predicting Periprocedural Complications During Percutaneous Coronary Interventions of Chronic Total Occlusions: The Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) Complications Score
Danek, Barbara Anna; Karatasakis, Aris; Karmpaliotis, Dimitri; Alaswad, Khaldoon; Yeh, Robert W.; Jaffer, Farouc A.; Patel, Mitul P.; Mahmud, Ehtisham; Lombardi, William L.; Wyman, Michael R.; Grantham, J. Aaron; Doing, Anthony; Kandzari, David E.; Lembo, Nicholas J.; Garcia, Santiago; Toma, Catalin; Moses, Jeffrey W.; Kirtane, Ajay J.; Parikh, Manish A.; Ali, Ziad A.; Karacsonyi, Judit; Rangan, Bavana V.; Thompson, Craig A.; Banerjee, Subhash; Brilakis, Emmanouil S. (John Wiley and Sons Inc., 2016)Background: High success rates are achievable for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using the hybrid approach, but periprocedural complications remain of concern. Although scores ... -
Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis
Khamis, Ramzi Y; Woollard, Kevin J.; Hyde, Gareth D.; Boyle, Joseph J; Bicknell, Colin; Chang, Shang-Hung; Malik, Talat H; Hara, Tetsuya; Mauskapf, Adam; Granger, David W; Johnson, Jason L.; Ntziachristos, Vasilis; Matthews, Paul M; Jaffer, Farouc A; Haskard, Dorian O (Nature Publishing Group, 2016)We aimed to develop a quantitative antibody-based near infrared fluorescence (NIRF) approach for the imaging of oxidized LDL in atherosclerosis. LO1, a well- characterized monoclonal autoantibody that reacts with ... -
Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring
Kessinger, Chase W.; Kim, Jin Won; Henke, Peter K.; Thompson, Brian; McCarthy, Jason R.; Hara, Tetsuya; Sillesen, Martin; Margey, Ronan J. P.; Libby, Peter; Weissleder, Ralph; Lin, Charles P.; Jaffer, Farouc A. (Public Library of Science, 2015)Despite anticoagulation therapy, up to one-half of patients with deep vein thrombosis (DVT) will develop the post-thrombotic syndrome (PTS). Improving the long-term outcome of DVT patients at risk for PTS will therefore ... -
Use of Intravascular Imaging During Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From a Contemporary Multicenter Registry
Karacsonyi, Judit; Alaswad, Khaldoon; Jaffer, Farouc A.; Yeh, Robert W.; Patel, Mitul; Bahadorani, John; Karatasakis, Aris; Danek, Barbara A.; Doing, Anthony; Grantham, J. Aaron; Karmpaliotis, Dimitri; Moses, Jeffrey W.; Kirtane, Ajay; Parikh, Manish; Ali, Ziad; Lombardi, William L.; Kandzari, David E.; Lembo, Nicholas; Garcia, Santiago; Wyman, Michael R.; Alame, Aya; Nguyen‐Trong, Phuong‐Khanh J.; Resendes, Erica; Kalsaria, Pratik; Rangan, Bavana V.; Ungi, Imre; Thompson, Craig A.; Banerjee, Subhash; Brilakis, Emmanouil S. (John Wiley and Sons Inc., 2016)Background: Intravascular imaging can facilitate chronic total occlusion (CTO) percutaneous coronary intervention. Methods and Results: We examined the frequency of use and outcomes of intravascular imaging among 619 CTO ...