Browsing by Author "Torres-Arzayus, Maria I"

Now showing items 1-2 of 2

    • Ret inhibition decreases growth and metastatic potential of estrogen receptor positive breast cancer cells 

      Gattelli, Albana; Nalvarte, Ivan; Boulay, Anne; Roloff, Tim C; Schreiber, Martin; Carragher, Neil; Macleod, Kenneth K; Schlederer, Michaela; Lienhard, Susanne; Kenner, Lukas; Torres-Arzayus, Maria I; Hynes, Nancy E (Blackwell Publishing Ltd, 2013)
      We show that elevated levels of Ret receptor are found in different sub-types of human breast cancers and that high Ret correlates with decreased metastasis-free survival. The role of Ret in ER+ breast cancer models was ...

    • Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts 

      Pfefferle, Adam D; Herschkowitz, Jason I; Usary, Jerry; Harrell, Joshua Chuck; Spike, Benjamin T; Adams, Jessica R; Torres-Arzayus, Maria I; Brown, Myles; Egan, Sean E; Wahl, Geoffrey M; Rosen, Jeffrey M; Perou, Charles M (BioMed Central, 2013)
      Background: Human breast cancer is a heterogeneous disease consisting of multiple molecular subtypes. Genetically engineered mouse models are a useful resource for studying mammary cancers in vivo under genetically controlled ...