Browsing by Author "Rui, Xianliang"

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    • Crystal Structure of the Complete Integrin αVβ3 Ectodomain Plus an α/β Transmembrane Fragment 

      Mahalingham, Bhuvaneshwari; Borrelli, Laura Ann; Rysiok, Thomas; Müller-Pompalla, Dirk; Goodman, Simon L.; Xiong, Jian-Ping; Alonso, Jose Luis; Rui, Xianliang; Anand, Saurabh; Hyman, Bradley Theodore; Arnaout, M. Amin (The Rockefeller University Press, 2009)
      We determined the crystal structure of 1TM-αVβ3, which represents the complete unconstrained ectodomain plus short C-terminal transmembrane stretches of the αV and β3 subunits. 1TM-αVβ3 is more compact and less active in ...