Browsing by Author "Brill, Alexander"

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    • ADAMTS13: A New Link Between Thrombosis and Inflammation 

      Chauhan, Anil K.; Kisucka, Janka; Brill, Alexander; Walsh, Meghan T.; Scheiflinger, Friedrich; Wagner, Denisa D. (The Rockefeller University Press, 2008)
      von Willebrand factor (VWF) levels are elevated and a disintegrin-like and metalloprotease with thrombospondin type I repeats–13 (ADAMTS13) activity is decreased in both acute and chronic inflammation. We hypothesized that ...

    • Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo 

      von Brühl, Marie-Luise; Stark, Konstantin; Steinhart, Alexander; Chandraratne, Sue; Konrad, Ildiko; Lorenz, Michael; Khandoga, Alexander; Tirniceriu, Anca; Coletti, Raffaele; Köllnberger, Maria; Byrne, Robert A.; Laitinen, Iina; Walch, Axel; Brill, Alexander; Pfeiler, Susanne; Manukyan, Davit; Braun, Siegmund; Lange, Philipp; Riegger, Julia; Ware, Jerry; Eckart, Annekathrin; Haidari, Selgai; Rudelius, Martina; Schulz, Christian; Echtler, Katrin; Brinkmann, Volker; Schwaiger, Markus; Preissner, Klaus T.; Wagner, Denisa D.; Mackman, Nigel; Engelmann, Bernd; Massberg, Steffen (The Rockefeller University Press, 2012)
      Deep vein thrombosis (DVT) is a major cause of cardiovascular death. The sequence of events that promote DVT remains obscure, largely as a result of the lack of an appropriate rodent model. We describe a novel mouse model ...