Now showing items 1-4 of 4

    • Effects of ventilation strategy on distribution of lung inflammatory cell activity 

      de Prost, Nicolas; Costa, Eduardo L; Wellman, Tyler; Musch, Guido; Tucci, Mauro R; Winkler, Tilo; Harris, R Scott; Venegas, Jose G; Kavanagh, Brian P; Vidal Melo, Marcos F (BioMed Central, 2013)
      Introduction: Leukocyte infiltration is central to the development of acute lung injury, but it is not known how mechanical ventilation strategy alters the distribution or activation of inflammatory cells. We explored how ...
    • Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study 

      Ladha, Karim; Vidal Melo, Marcos F; McLean, Duncan J; Wanderer, Jonathan P; Grabitz, Stephanie D; Kurth, Tobias; Eikermann, Matthias (BMJ Publishing Group Ltd., 2015)
      Objective: To evaluate the effects of intraoperative protective ventilation on major postoperative respiratory complications and to define safe intraoperative mechanical ventilator settings that do not translate into an ...
    • Modeling \(^{18}F-FDG\) Kinetics during Acute Lung Injury: Experimental Data and Estimation Errors 

      Dittrich, A. Susanne; Winkler, Tilo; Wellman, Tyler James; de Prost, Nicolas; Musch, Guido; Harris, Robert Scott; Vidal Melo, Marcos Francisco (Public Library of Science, 2012)
      Background: There is increasing interest in Positron Emission Tomography (PET) of 2-deoxy-2-[18F]flouro-D-glucose (\(^{18}F-FDG\)) to evaluate pulmonary inflammation during acute lung injury (ALI). We assessed the effect ...
    • Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation 

      Harris, Robert Scott; Fujii-Rios, Hanae; Winkler, Tilo; Musch, Guido; Vidal Melo, Marcos Francisco; Venegas, Jose Gabriel (Public Library of Science, 2012)
      Background: Imaging studies have demonstrated that ventilation during bronchoconstriction in subjects with asthma is patchy with large ventilation defective areas (Vdefs). Based on a theoretical model, we postulated that ...