Browsing by Author "Eikermann, Matthias"
Now showing items 1-8 of 8
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Codifying healthcare – big data and the issue of misclassification
Ladha, Karim S.; Eikermann, Matthias (BioMed Central, 2015)The rise of electronic medical records has led to a proliferation of large observational studies that examine the perioperative period. In contrast to randomized controlled trials, these studies have the ability to provide ... -
The Deyo-Charlson and Elixhauser-van Walraven Comorbidity Indices as predictors of mortality in critically ill patients
Ladha, Karim S; Zhao, Kevin; Quraishi, Sadeq A; Kurth, Tobias; Eikermann, Matthias; Kaafarani, Haytham M A; Klein, Eric N; Seethala, Raghu; Lee, Jarone (BMJ Publishing Group, 2015)Objectives: Our primary objective was to compare the utility of the Deyo-Charlson Comorbidity Index (DCCI) and Elixhauser-van Walraven Comorbidity Index (EVCI) to predict mortality in intensive care unit (ICU) patients. ... -
Effects of obstructive sleep apnoea risk on postoperative respiratory complications: protocol for a hospital-based registry study
Shin, Christina H; Zaremba, Sebastian; Devine, Scott; Nikolov, Milcho; Kurth, Tobias; Eikermann, Matthias (BMJ Publishing Group, 2016)Introduction: Obstructive sleep apnoea (OSA), the most common type of sleep-disordered breathing, is associated with significant immediate and long-term morbidity, including fragmented sleep and impaired daytime functioning, ... -
Etomidate and Ketamine: Residual Motor and Adrenal Dysfunction that Persist beyond Recovery from Loss of Righting Reflex in Rats
Diaz-Gil, Daniel; Mueller, Noomi; Moreno-Duarte, Ingrid; Lin, Hsin; Ayata, Cenk; Cusin, Cristina; Cotten, Joseph F.; Eikermann, Matthias (MDPI, 2014)We tested the hypothesis that etomidate and ketamine produce residual effects that modify functional mobility (measured by the balance beam test) and adrenal function (adrenocorticotropic hormone (ACTH) stimulation) ... -
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study
Grosse-Sundrup, Martina; Henneman, Justin P; Sandberg, Warren S; Bateman, Brian Thomas; Uribe, Jose Villa; Nguyen, Nicole Thuy; Ehrenfeld, Jesse M.; Martinez, Elizabeth; Kurth, Tobias; Eikermann, Matthias (BMJ Publishing Group Ltd., 2012)Objective: To determine whether use of intermediate acting neuromuscular blocking agents during general anesthesia increases the incidence of postoperative respiratory complications. Design: Prospective, propensity score ... -
Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study
Ladha, Karim; Vidal Melo, Marcos F; McLean, Duncan J; Wanderer, Jonathan P; Grabitz, Stephanie D; Kurth, Tobias; Eikermann, Matthias (BMJ Publishing Group Ltd., 2015)Objective: To evaluate the effects of intraoperative protective ventilation on major postoperative respiratory complications and to define safe intraoperative mechanical ventilator settings that do not translate into an ... -
Perioperative sleep apnea: a real problem or did we invent a new disease?
Zaremba, Sebastian; Mojica, James E.; Eikermann, Matthias (F1000Research, 2016)Depending on the subpopulation, obstructive sleep apnea (OSA) can affect more than 75% of surgical patients. An increasing body of evidence supports the association between OSA and perioperative complications, but some ... -
Surgical Intensive Care Unit Optimal Mobilisation Score (SOMS) trial: a protocol for an international, multicentre, randomised controlled trial focused on goal-directed early mobilisation of surgical ICU patients
Meyer, Matthew J; Stanislaus, Anne B; Lee, Jarone; Waak, Karen; Ryan, Cheryl; Saxena, Richa; Ball, Stephanie; Schmidt, Ulrich; Poon, Trudy; Piva, Simone; Walz, Matthias; Talmor, Daniel S; Blobner, Manfred; Latronico, Nicola; Eikermann, Matthias (BMJ Publishing Group, 2013)Introduction: Immobilisation in the intensive care unit (ICU) leads to muscle weakness and is associated with increased costs and long-term functional disability. Previous studies showed early mobilisation of medical ICU ...