Now showing items 1-20 of 68

    • Adolescent Diet Quality and Cardiovascular Disease Risk Factors and Incident Cardiovascular Disease in Middle‐Aged Women 

      Dahm, Christina C.; Chomistek, Andrea K.; Jakobsen, Marianne Uhre; Mukamal, Kenneth J.; Eliassen, A. Heather; Sesso, Howard D.; Overvad, Kim; Willett, Walter C.; Rimm, Eric B.; Chiuve, Stephanie E. (John Wiley and Sons Inc., 2016)
      Background: Primary prevention of cardiovascular disease (CVD) focuses on treatment of risk factors, including hypercholesterolemia, hypertension, and type 2 diabetes mellitus. We investigated whether a healthy diet in ...
    • Alcohol Consumption, Mediating Biomarkers, and Risk of Type 2 Diabetes Among Middle-Aged Women 

      Beulens, Joline W.J.; Rimm, Eric B.; Hu, Frank B.; Hendriks, Henk F.J.; Mukamal, Ken J. (American Diabetes Association, 2008)
      OBJECTIVE—The purpose of this study was to investigate whether adiponectin concentrations and biomarkers of inflammation, endothelial dysfunction, and insulin resistance mediate the association between alcohol consumption ...
    • Apolipoprotein C-III as a Potential Modulator of the Association Between HDL-Cholesterol and Incident Coronary Heart Disease 

      Jensen, Majken Karoline; Rimm, Eric B.; Furtado, Jeremy Daniel; Sacks, Frank Martin (Blackwell Publishing Ltd, 2012)
      Background: High-density lipoproteins (HDL) are structurally and metabolically heterogeneous and subclasses with differential effects on coronary heart disease (CHD) might exist. Apolipoprotein (apo) C-III, a small ...
    • Apolipoprotein E in VLDL and LDL With Apolipoprotein C‐III is Associated With a Lower Risk of Coronary Heart Disease 

      Mendivil, Carlos O.; Rimm, Eric B.; Furtado, Jeremy; Sacks, Frank M. (Blackwell Publishing Ltd, 2013)
      Background: Low‐density lipoprotein (LDL) with apolipoprotein C‐III (apoC‐III) is the lipoprotein species that most strongly predicts initial and recurring coronary heart disease (CHD) events in several cohorts. Thus, a ...
    • Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data 

      Holmes, Michael V; Dale, Caroline E; Zuccolo, Luisa; Silverwood, Richard J; Guo, Yiran; Ye, Zheng; Prieto-Merino, David; Dehghan, Abbas; Trompet, Stella; Wong, Andrew; Cavadino, Alana; Drogan, Dagmar; Padmanabhan, Sandosh; Li, Shanshan; Yesupriya, Ajay; Leusink, Maarten; Sundstrom, Johan; Hubacek, Jaroslav A; Pikhart, Hynek; Swerdlow, Daniel I; Panayiotou, Andrie G; Borinskaya, Svetlana A; Finan, Chris; Shah, Sonia; Kuchenbaecker, Karoline B; Shah, Tina; Engmann, Jorgen; Folkersen, Lasse; Eriksson, Per; Ricceri, Fulvio; Melander, Olle; Sacerdote, Carlotta; Gamble, Dale M; Rayaprolu, Sruti; Ross, Owen A; McLachlan, Stela; Vikhireva, Olga; Sluijs, Ivonne; Scott, Robert A; Adamkova, Vera; Flicker, Leon; van Bockxmeer, Frank M; Power, Christine; Marques-Vidal, Pedro; Meade, Tom; Marmot, Michael G; Ferro, Jose M; Paulos-Pinheiro, Sofia; Humphries, Steve E; Talmud, Philippa J; Leach, Irene Mateo; Verweij, Niek; Linneberg, Allan; Skaaby, Tea; Doevendans, Pieter A; Cramer, Maarten J; van der Harst, Pim; Klungel, Olaf H; Dowling, Nicole F; Dominiczak, Anna F; Kumari, Meena; Nicolaides, Andrew N; Weikert, Cornelia; Boeing, Heiner; Ebrahim, Shah; Gaunt, Tom R; Price, Jackie F; Lannfelt, Lars; Peasey, Anne; Kubinova, Ruzena; Pajak, Andrzej; Malyutina, Sofia; Voevoda, Mikhail I; Tamosiunas, Abdonas; Maitland-van der Zee, Anke H; Norman, Paul E; Hankey, Graeme J; Bergmann, Manuela M; Hofman, Albert; Franco, Oscar H; Cooper, Jackie; Palmen, Jutta; Spiering, Wilko; de Jong, Pim A; Kuh, Diana; Hardy, Rebecca; Uitterlinden, Andre G; Ikram, M Arfan; Ford, Ian; Hyppönen, Elina; Almeida, Osvaldo P; Wareham, Nicholas J; Khaw, Kay-Tee; Hamsten, Anders; Husemoen, Lise Lotte N; Tjønneland, Anne; Tolstrup, Janne S; Rimm, Eric; Beulens, Joline W J; Verschuren, W M Monique; Onland-Moret, N Charlotte; Hofker, Marten H; Wannamethee, S Goya; Whincup, Peter H; Morris, Richard; Vicente, Astrid M; Watkins, Hugh; Farrall, Martin; Jukema, J Wouter; Meschia, James; Cupples, L Adrienne; Sharp, Stephen J; Fornage, Myriam; Kooperberg, Charles; LaCroix, Andrea Z; Dai, James Y; Lanktree, Matthew B; Siscovick, David S; Jorgenson, Eric; Spring, Bonnie; Coresh, Josef; Li, Yun R; Buxbaum, Sarah G; Schreiner, Pamela J; Ellison, R Curtis; Tsai, Michael Y; Patel, Sanjay R; Redline, Susan; Johnson, Andrew D; Hoogeveen, Ron C; Hakonarson, Hakon; Rotter, Jerome I; Boerwinkle, Eric; de Bakker, Paul I W; Kivimaki, Mika; Asselbergs, Folkert W; Sattar, Naveed; Lawlor, Debbie A; Whittaker, John; Davey Smith, George; Mukamal, Kenneth; Psaty, Bruce M; Wilson, James G; Lange, Leslie A; Hamidovic, Ajna; Hingorani, Aroon D; Nordestgaard, Børge G; Bobak, Martin; Leon, David A; Langenberg, Claudia; Palmer, Tom M; Reiner, Alex P; Keating, Brendan J; Dudbridge, Frank; Casas, Juan P (BMJ Publishing Group Ltd., 2014)
      Objective: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. Design: Mendelian randomisation meta-analysis of ...
    • Association Between Passive and Active Smoking and Incident Type 2 Diabetes in Women 

      Zhang, Luxia; Curhan, Gary Craig; Hu, Frank B.; Rimm, Eric B.; Forman, John Phillip (American Diabetes Association, 2011)
      OBJECTIVE: Accumulating evidence has identified a positive association between active smoking and the risk of diabetes, but previous studies had limited information on passive smoking or changes in smoking behaviors over ...
    • Association of Plasma Phospholipid Long-Chain Omega-3 Fatty Acids With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study 

      Wu, J. H. Y.; Lemaitre, R. N.; King, I. B.; Song, X.; Sacks, Frank Martin; Rimm, Eric Bruce; Heckbert, S. R.; Siscovick, D. S.; Mozaffarian, D (Ovid Technologies (Wolters Kluwer Health), 2012)
      BACKGROUND: Experimental studies suggest that long-chain n-3 polyunsaturated fatty acids (n-3 PUFAs) may reduce the risk of atrial fibrillation (AF). Prior studies evaluating fish or n-3 PUFA consumption from dietary ...
    • Associations of Bowel Movement Frequency with Risk of Cardiovascular Disease and Mortality among US Women 

      Ma, Wenjie; Li, Yanping; Heianza, Yoriko; Staller, Kyle D.; Chan, Andrew T.; Rimm, Eric B.; Rexrode, Kathryn M.; Qi, Lu (Nature Publishing Group, 2016)
      Emerging evidence suggests a potential impact of gastrointestinal function on cardiometabolic risk. Abnormal bowel movements have been related to various cardiovascular risk factors such as dyslipidemia, hypertension, ...
    • Associations of Plasma Phospholipid and Dietary Alpha Linolenic Acid With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study 

      Fretts, Amanda M.; Mozaffarian, Dariush; Siscovick, David S.; Heckbert, Susan R.; McKnight, Barbara; King, Irena B.; Rimm, Eric B.; Psaty, Bruce M.; Sacks, Frank Martin; Song, Xiaoling; Spiegelman, Donna Lynn; Lemaitre, Rozenn N. (Blackwell Publishing Ltd, 2013)
      Background: Few studies have examined the relationship of α‐linolenic acid (ALA 18:3n‐3), an intermediate‐chain essential n‐3 polyunsaturated fatty acid derived from plants and vegetable oils, with incident atrial fibrillation ...
    • Associations of Trauma Exposure and Posttraumatic Stress Symptoms With Venous Thromboembolism Over 22 Years in Women 

      Sumner, Jennifer A.; Kubzansky, Laura D.; Kabrhel, Christopher; Roberts, Andrea L.; Chen, Qixuan; Winning, Ashley; Gilsanz, Paola; Rimm, Eric B.; Glymour, Maria M.; Koenen, Karestan C. (John Wiley and Sons Inc., 2016)
      Background: Trauma exposure and posttraumatic stress disorder (PTSD) have been linked to myocardial infarction and stroke in women, with biological and behavioral mechanisms implicated in underlying risk. The third most ...
    • Bachelors, Divorcees, and Widowers: Does Marriage Protect Men from Type 2 Diabetes? 

      Cornelis, Marilyn C.; Chiuve, Stephanie E.; Glymour, M. Maria; Chang, Shun-Chiao; Tchetgen Tchetgen, Eric J.; Liang, Liming; Koenen, Karestan C.; Rimm, Eric B.; Kawachi, Ichiro; Kubzansky, Laura D. (Public Library of Science, 2014)
      While research has suggested that being married may confer a health advantage, few studies to date have investigated the role of marital status in the development of type 2 diabetes. We examined whether men who are not ...
    • C-Reactive Protein (CRP) Gene Polymorphisms, CRP Levels, and Risk of Incident Coronary Heart Disease in Two Nested Case-Control Studies 

      Pai, Jennifer Kai-cha; Mukamal, Ken J.; Rexrode, Kathryn Marian; Rimm, Eric B. (Public Library of Science, 2008)
      Background: C-reactive protein (CRP), an acute phase reactant and marker of inflammation, has been shown to predict risk of incident cardiovascular events. However, few studies have comprehensively examined six common ...
    • Changes in Alcohol Consumption and Subsequent Risk of Type 2 Diabetes in Men 

      Joosten, Michel M.; Chiuve, Stephanie Elizabeth; Mukamal, Kenneth J.; Hu, Frank B.; Hendriks, Henk F. J.; Rimm, Eric B. (American Diabetes Association, 2011)
      OBJECTIVE: The objective of this study was to investigate the association of 4-year changes in alcohol consumption with a subsequent risk of type 2 diabetes. RESEARCH DESIGN AND METHODS: We prospectively examined 38,031 ...
    • Changes in Intake of Fruits and Vegetables and Weight Change in US Men and Women Followed for up to 24 Years: Analysis from Three Prospective Cohort Studies 

      Bertoia, Monica; Mukamal, Kenneth J.; Cahill, Leah; Hou, Tao; Ludwig, David S.; Mozaffarian, Dariush; Willett, Walter C.; Hu, Frank B.; Rimm, Eric Bruce (Public Library of Science, 2015)
      Background Current dietary guidelines recommend eating a variety of fruits and vegetables. However, based on nutrient composition, some particular fruits and vegetables may be more or less beneficial for maintaining or ...
    • Circulating Omega‐3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study 

      Virtanen, Jyrki K.; Siscovick, David S.; Lemaitre, Rozenn N.; Longstreth, William T.; Spiegelman, Donna; Rimm, Eric B.; King, Irena B.; Mozaffarian, Dariush (Blackwell Publishing Ltd, 2013)
      Background: Consumption of tuna or other broiled or baked fish, but not fried fish, is associated with fewer subclinical brain abnormalities on magnetic resonance imaging (MRI). We investigated the association between ...
    • Comparison of Self-Reported and Accelerometer-Assessed Physical Activity in Older Women 

      Shiroma, Eric J.; Cook, Nancy R.; Manson, JoAnn E.; Buring, Julie E.; Rimm, Eric B.; Lee, I-Min (Public Library of Science, 2015)
      Background: Self-reported physical activity measures continue to be validated against accelerometers; however, the absence of standardized, accelerometer moderate-to-vigorous physical activity (MVPA) definitions has made ...
    • Diet-Quality Scores and the Risk of Type 2 Diabetes in Men 

      de Koning, Lawrence; Chiuve, Stephanie Elizabeth; Fung, Teresa Toiyee; Willett, Walter C.; Rimm, Eric B.; Hu, Frank B. (American Diabetes Association, 2011)
      Objective: To 1) compare associations of diet-quality scores, which were inversely associated with cardiovascular disease, with incident type 2 diabetes and 2) test for differences in absolute-risk reduction across various ...
    • Dietary fiber intake and mortality among survivors of myocardial infarction: prospective cohort study 

      Li, Shanshan; Flint, Alan; Pai, Jennifer K; Forman, John P; Hu, Frank B; Willett, Walter C; Rexrode, Kathryn M; Mukamal, Kenneth J; Rimm, Eric B (BMJ Publishing Group Ltd., 2014)
      Objective: To evaluate the associations of dietary fiber after myocardial infarction (MI) and changes in dietary fiber intake from before to after MI with all cause and cardiovascular mortality. Design: Prospective cohort ...
    • Dietary flavonoid intake and incidence of erectile dysfunction1 

      Cassidy, Aedín; Franz, Mary; Rimm, Eric B (American Society for Nutrition, 2016)
      Background: The predominant etiology for erectile dysfunction (ED) is vascular, but limited data are available on the role of diet. A higher intake of several flavonoids reduces diabetes and cardiovascular disease risk, ...
    • Dietary flavonoid intake and risk of incident depression in midlife and older women123 

      Chang, Shun-Chiao; Cassidy, Aedin; Willett, Walter C; Rimm, Eric B; O’Reilly, Eilis J; Okereke, Olivia I (American Society for Nutrition, 2016)
      Background: The impact of dietary flavonoid intakes on risk of depression is unclear. Objective: We prospectively examined associations between estimated habitual intakes of dietary flavonoids and depression risk. Design: ...