Browsing by Author "Jourdain, Gonzague"
Now showing items 1-8 of 8
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Cost-Effectiveness of Early Infant HIV Diagnosis of HIV-Exposed Infants and Immediate Antiretroviral Therapy in HIV-Infected Children under 24 Months in Thailand
Collins, Intira Jeannie; Cairns, John; Ngo-Giang-Huong, Nicole; Sirirungsi, Wasna; Leechanachai, Pranee; Le Coeur, Sophie; Samleerat, Tanawan; Kamonpakorn, Nareerat; Mekmullica, Jutarat; Jourdain, Gonzague; Lallemant, Marc (Public Library of Science, 2014)Background: HIV-infected infants have high risk of death in the first two years of life if untreated. WHO guidelines recommend early infant HIV diagnosis (EID) of all HIV-exposed infants and immediate antiretroviral therapy ... -
Estimating the Timing of Mother-to-Child Transmission of the Human Immunodeficiency Virus Type 1 Using a Viral Molecular Evolution Model
Chaillon, Antoine; Samleerat, Tanawan; Zoveda, Faustine; Ballesteros, Sébastien; Moreau, Alain; Ngo-Giang-Huong, Nicole; Jourdain, Gonzague; Gianella, Sara; Lallemant, Marc; Depaulis, Frantz; Barin, Francis (Public Library of Science, 2014)Background: Mother-to-child transmission (MTCT) is responsible for most pediatric HIV-1 infections worldwide. It can occur during pregnancy, labor, or breastfeeding. Numerous studies have used coalescent and molecular clock ... -
Haematological Safety of Perinatal Zidovudine in Pregnant HIV-1–Infected Women in Thailand: Secondary Analysis of a Randomized Trial
Briand, Nelly; Lallemant, Marc Jean; Jourdain, Gonzague Joseph Albert; Techapalokul, Somnuek; Tunthanathip, Preecha; Suphanich, Surachet; Chanpoo, Truengta; Traisathit, Patrinee; McIntosh, Kenneth; Coeur, Sophie Le (Public Library of Science, 2007)Objectives: To respond to the primary safety objective of the Perinatal HIV Prevention Trial 1 (PHPT-1) by studying the evolution of haematological parameters according to zidovudine exposure duration in HIV-1−infected ... -
Laboratory and Clinical Predictors of Disease Progression following Initiation of Combination Therapy in HIV-Infected Adults in Thailand
Duong, Trinh; Jourdain, Gonzague Joseph Albert; Ngo-Giang-Huong, Nicole; Le Cœur, Sophie; Kantipong, Pacharee; Buranabanjasatean, Sudanee; Leenasirimakul, Prattana; Ariyadej, Sriprapar; Tansuphasawasdikul, Somboon; Thongpaen, Suchart; Lallemant, Marc Jean (Public Library of Science, 2012)Background: Data on determinants of long-term disease progression in HIV-infected patients on antiretroviral therapy (ART) are limited in low and middle-income settings. Methods: Effects of current CD4 count, viral load ... -
Long-Term Hepatitis B Virus (HBV) Response to Lamivudine-Containing Highly Active Antiretroviral Therapy in HIV-HBV Co-Infected Patients in Thailand
Khamduang, Woottichai; Gaudy-Graffin, Catherine; Ngo-Giang-Huong, Nicole; Jourdain, Gonzague Joseph Albert; Moreau, Alain; Luekamlung, Nuananong; Halue, Guttiga; Buranawanitchakorn, Yuwadee; Kunkongkapan, Sura; Buranabanjasatean, Sudanee; Lallemant, Marc Jean; Sirirungsi, Wasna; Goudeau, Alain (Public Library of Science, 2012)Background: Approximately 4 million of people are co-infected with HIV and Hepatitis B virus (HBV). In resource-limited settings, the majority of HIV-infected patients initiate first-line highly active antiretroviral therapy ... -
Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV
Sripan, Patumrat; Le Coeur, Sophie; Amzal, Billy; Ingsrisawang, Lily; Traisathit, Patrinee; Ngo-Giang-Huong, Nicole; McIntosh, Kenneth; Cressey, Tim R.; Sangsawang, Suraphan; Rawangban, Boonsong; Kanjanavikai, Prateep; Tréluyer, Jean-Marc; Jourdain, Gonzague; Lallemant, Marc; Urien, Saïk (Public Library of Science, 2015)Background: Antiretroviral treatments decrease HIV mother-to-child transmission through pre/post exposure prophylaxis and reduction of maternal viral load. We modeled in-utero and intra-partum HIV transmissions to investigate ... -
Prevention of mother-to-child transmission of hepatitis B virus: a phase III, placebo-controlled, double-blind, randomized clinical trial to assess the efficacy and safety of a short course of tenofovir disoproxil fumarate in women with hepatitis B virus e-antigen
Jourdain, Gonzague; Ngo-Giang-Huong, Nicole; Cressey, Tim R.; Hua, Lei; Harrison, Linda; Tierney, Camlin; Salvadori, Nicolas; Decker, Luc; Traisathit, Patrinee; Sirirungsi, Wasna; Khamduang, Woottichai; Bowonwatanuwong, Chureeratana; Puthanakit, Thanyawee; Siberry, George K.; Watts, Diane Heather; Murphy, Trudy V.; Achalapong, Jullapong; Hongsiriwon, Suchat; Klinbuayaem, Virat; Thongsawat, Satawat; Chung, Raymond T.; Pol, Stanislas; Chotivanich, Nantasak (BioMed Central, 2016)Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. In Thailand, 6-7 % of adults are chronically infected with HBV. The risk of mother-to-child transmission (MTCT) of HBV has ... -
Switching HIV Treatment in Adults Based on CD4 Count Versus Viral Load Monitoring: A Randomized, Non-Inferiority Trial in Thailand
Jourdain, Gonzague; Le Cœur, Sophie; Ngo-Giang-Huong, Nicole; Traisathit, Patrinee; Cressey, Tim R.; Fregonese, Federica; Leurent, Baptiste; Collins, Intira J.; Techapornroong, Malee; Banchongkit, Sukit; Buranabanjasatean, Sudanee; Halue, Guttiga; Nilmanat, Ampaipith; Luekamlung, Nuananong; Klinbuayaem, Virat; Chutanunta, Apichat; Kantipong, Pacharee; Bowonwatanuwong, Chureeratana; Lertkoonalak, Rittha; Leenasirimakul, Prattana; Tansuphasawasdikul, Somboon; Sang-a-gad, Pensiriwan; Pathipvanich, Panita; Thongbuaban, Srisuda; Wittayapraparat, Pakorn; Eiamsirikit, Naree; Buranawanitchakorn, Yuwadee; Yutthakasemsunt, Naruepon; Winiyakul, Narong; Decker, Luc; Barbier, Sylvaine; Koetsawang, Suporn; Sirirungsi, Wasna; McIntosh, Kenneth; Thanprasertsuk, Sombat; Lallemant, Marc (Public Library of Science, 2013)Background: Viral load (VL) is recommended for monitoring the response to highly active antiretroviral therapy (HAART) but is not routinely available in most low- and middle-income countries. The purpose of the study was ...