Browsing by Author "Yee, Christina"

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    • Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function 

      Kumar, Lalit; Chou, Janet; Yee, Christina S.K.; Borzutzky, Arturo; Vollmann, Elisabeth H.; von Andrian, Ulrich H.; Park, Shin-Young; Hollander, Georg; Manis, John P.; Poliani, P. Luigi; Geha, Raif S. (The Rockefeller University Press, 2014)
      Lrrc8a is a ubiquitously expressed gene that encodes a leucine-rich repeat (LRR)–containing protein detected at higher levels on the surface of thymocytes than on other immune cells. We generated Lrrc8a−/− mice to investigate ...