Browsing by Author "Schorderet, Patrick"

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    • Chromatin topology is coupled to Polycomb group protein subnuclear organization 

      Wani, Ajazul H.; Boettiger, Alistair N.; Schorderet, Patrick; Ergun, Ayla; Münger, Christine; Sadreyev, Ruslan I.; Zhuang, Xiaowei; Kingston, Robert E.; Francis, Nicole J. (Nature Publishing Group, 2016)
      The genomes of metazoa are organized at multiple scales. Many proteins that regulate genome architecture, including Polycomb group (PcG) proteins, form subnuclear structures. Deciphering mechanistic links between protein ...

    • NEAT: a framework for building fully automated NGS pipelines and analyses 

      Schorderet, Patrick (BioMed Central, 2016)
      Background: The analysis of next generation sequencing (NGS) has become a standard task for many laboratories in the life sciences. Though there exists several tools to support users in the manipulation of such datasets ...