Browsing by Author "Evans, Conor"
Now showing items 1-8 of 8
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Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine
Evans, Conor L.; Xie, Xiaoliang Sunney (Annual Reviews, 2008)Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging technique that is capable of real-time, nonperturbative examination of living cells and organisms based on molecular vibrational spectroscopy. ... -
Comprehensive Evaluation of Peripheral Nerve Regeneration in the Acute Healing Phase Using Tissue Clearing and Optical Microscopy in a Rodent Model
Jung, Yookyung; Ng, Joanna H.; Keating, Cameron P.; Senthil-Kumar, Prabhu; Zhao, Jie; Randolph, Mark A.; Winograd, Jonathan M.; Evans, Conor L. (Public Library of Science, 2014)Peripheral nerve injury (PNI), a common injury in both the civilian and military arenas, is usually associated with high healthcare costs and with patients enduring slow recovery times, diminished quality of life, and ... -
In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin
Wang, Hequn; Osseiran, Sam; Igras, Vivien; Nichols, Alexander J.; Roider, Elisabeth M.; Pruessner, Joachim; Tsao, Hensin; Fisher, David E.; Evans, Conor L. (Nature Publishing Group, 2016)Melanoma is the most deadly form of skin cancer with a yearly global incidence over 232,000 patients. Individuals with fair skin and red hair exhibit the highest risk for developing melanoma, with evidence suggesting the ... -
Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti-Stokes Raman scattering microscopy –normal function and response to cryotherapy
Jung, Yookyung; Tam, Joshua; Jalian, H. Ray; Anderson, R. Rox; Evans, Conor L. (2014)Sebaceous glands perform complex functions, and are centrally involved in the pathogenesis of acne vulgaris. Current techniques for studying sebaceous glands are mostly static in nature, whereas the gland’s main function ... -
Longitudinal, label-free, quantitative tracking of cell death and viability in a 3D tumor model with OCT
Jung, Yookyung; Klein, Oliver J.; Wang, Hequn; Evans, Conor L. (Nature Publishing Group, 2016)Three-dimensional in vitro tumor models are highly useful tools for studying tumor growth and treatment response of malignancies such as ovarian cancer. Existing viability and treatment assessment assays, however, face ... -
PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro
Hung, Hsin-I; Klein, Oliver J.; Peterson, Sam W.; Rokosh, Sarah R.; Osseiran, Sam; Nowell, Nicholas H.; Evans, Conor L. (Nature Publishing Group, 2016)Photodynamic therapy regimens, which use light-activated molecules known as photosensitizers, are highly selective against many malignancies and can bypass certain challenging therapeutic resistance mechanisms. Photosensitizers ... -
Self-interference fluorescence microscopy: three dimensional fluorescence imaging without depth scanning
de Groot, Mattijs; Evans, Conor L.; de Boer, Johannes F. (Optical Society of America, 2012)We present a new method for high-resolution, three-dimensional fluorescence imaging. In contrast to beam-scanning confocal microscopy, where the laser focus must be scanned both laterally and axially to collect a volume, ... -
Transient alterations of cutaneous sensory nerve function by non-invasive cryolipolysis
Garibyan, Lilit; Cornelissen, Laura; Sipprell, William; Pruessner, Joachim; Elmariah, Sarina; Luo, Tuan; Lerner, Ethan A.; Jung, Yookyung; Evans, Conor; Zurakowski, David; Berde, Charles B.; Rox Anderson, R. (2015)Cryolipolysis is a non-invasive, skin cooling treatment for local fat reduction that causes prolonged hypoesthesia over the treated area. We tested the hypothesis that cryolipolysis can attenuate nociception of a range of ...