Now showing items 1-2 of 2

    • dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes 

      Korenjak, Michael; Kwon, Eunjeong; Morris, Robert T.; Anderssen, Endre; Amzallag, Arnaud; Ramaswamy, Sridhar; Dyson, Nicholas J. (Oxford University Press, 2014)
      dREAM complexes represent the predominant form of E2F/RBF repressor complexes in Drosophila. dREAM associates with thousands of sites in the fly genome but its mechanism of action is unknown. To understand the genomic ...
    • In Vivo Regulation of E2F1 by Polycomb Group Genes in Drosophila 

      Ji, Jun-Yuan; Miles, Wayne O.; Korenjak, Michael; Zheng, Yani; Dyson, Nicholas J. (Genetics Society of America, 2012)
      The E2F transcription factors are important regulators of the cell cycle whose function is commonly misregulated in cancer. To identify novel regulators of E2F1 activity in vivo, we used Drosophila to conduct genetic ...