Browsing by Author "Bernhardy, Andrea J."

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    • Copy Number Variation at the APOL1 Locus 

      Ruchi, Rupam; Genovese, Giulio; Lee, Jessica; Charoonratana, Victoria T.; Bernhardy, Andrea J.; Alper, Seth L.; Kopp, Jeffrey B.; Thadhani, Ravi; Friedman, David J.; Pollak, Martin R. (Public Library of Science, 2015)
      Two coding variants in the APOL1 gene (G1 and G2) explain most of the high rate of kidney disease in African Americans. APOL1-associated kidney disease risk inheritance follows an autosomal recessive pattern: The relative ...

    • Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo 

      Grgic, Ivica; Hofmeister, Andreas F.; Genovese, Giulio; Bernhardy, Andrea J.; Sun, Hua; Maarouf, Omar H.; Bijol, Vanesa; Pollak, Martin R.; Humphreys, Benjamin D. (2014)
      Identifying new biomarkers and therapeutic targets for podocytopathies such as focal segmental glomerulosclerosis (FSGS) requires a detailed analysis of transcriptional changes in podocytes over the course of disease. Here ...