Browsing by Author "Horton, Edward"
Now showing items 1-6 of 6
-
Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program
Jablonski, Kathleen A.; McAteer, Jarred B.; Franks, Paul W.; Mason, Clinton C.; Mather, Kieren; Goldberg, Ronald; Dabelea, Dana; Kahn, Steven E.; Arakaki, Richard F.; Shuldiner, Alan R.; Knowler, William C.; Florez, Jose Carlos; Horton, Edward S. (Public Library of Science, 2012)Common genetic variants have been recently associated with fasting glucose and insulin levels in white populations. Whether these associations replicate in pre-diabetes is not known. We extended these findings to the ... -
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: the Diabetes Prevention Program
Pollin, Toni I.; Isakova, Tamara; Jablonski, Kathleen A.; de Bakker, Paul I. W.; Taylor, Andrew; McAteer, Jarred; Pan, Qing; Horton, Edward S.; Delahanty, Linda M.; Altshuler, David; Shuldiner, Alan R.; Goldberg, Ronald B.; Florez, Jose Carlos; Franks, Paul W. (Public Library of Science, 2012)Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 ... -
Lifestyle Intervention Improves Heart Rate Recovery from Exercise in Adults with Type 2 Diabetes: Results from the Look AHEAD Study
Ribisl, Paul M.; Gaussoin, Sarah A.; Lang, Wei; Bahnson, Judy; Connelly, Stephanie A.; Horton, Edward S.; Jakicic, John M.; Killean, Tina; Kitzman, Dalane W.; Knowler, William C.; Stewart, Kerry J.; Look AHEAD Research Group (Hindawi Publishing Corporation, 2012)The primary aims of this paper were (1) to evaluate the influence of intensive lifestyle weight loss and exercise intervention (ILI) compared with diabetes support and education (DSE) upon Heart Rate Recovery (HRR) from ... -
Opposing Effects of Particle Pollution, Ozone, and Ambient Temperature on Arterial Blood Pressure
Luttmann-Gibson, Heike; de Souza, Celine; Foley, Christopher; Hoffmann, Barbara H.; Cohen, Allison Leigh; Zanobetti, Antonella; Suh MacIntosh, Helen H.; Coull, Brent Andrew; Schwartz, Joel David; Mittleman, Murray A.; Stone, Peter Howard; Horton, Edward S.; Gold, Diane R. (National Institute of Environmental Health Sciences, 2012)Background: Diabetes increases the risk of hypertension and orthostatic hypotension and raises the risk of cardiovascular death during heat waves and high pollution episodes. Objective: We examined whether short-term ... -
Pulse Wave Analysis by Applanation Tonometry for the Measurement of Arterial Stiffness
Doupis, John; Papanas, Nikolaos; Cohen, Alison; McFarlan, Lyndsay; Horton, Edward (Bentham Open, 2016)The aim of our study was to investigate the association between pulse wave velocity (PWV) and pulse wave analysis (PWA)-derived measurements for the evaluation of arterial stiffness. A total of 20 (7 male and 13 female) ... -
Young Hispanics at risk of type 2 diabetes display endothelial activation, subclinical inflammation and alterations of coagulation and fibrinolysis
Mendivil, Carlos O; Robles-Osorio, Ludivina; Horton, Edward S; Hamdy, Osama; Caballero, Augusto Enrique (BioMed Central, 2013)Background: Hispanics have a high rate of diabetes that exposes them to an increased risk of cardiovascular disease. We hypothesized that many of the pathophysiological mechanisms that cause atherosclerotic disease may be ...