Browsing by Author "Kikinis, Zora"
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Genetic contributions to changes of fiber tracts of ventral visual stream in 22q11.2 deletion syndrome
Kikinis, Zora; Makris, Nikos; Finn, Christine; Bouix, Sylvain; Lucia, Diandra; Coleman, Michael James; Tworog-Dube, Erica; Kikinis, Ron; Kucherlapati, Raju; Shenton, Martha Elizabeth; Kubicki, Marek R. (Springer Science + Business Media, 2013)Patients with 22q11.2 deletion syndrome (22q11.2DS) represent a population at high risk for developing schizophrenia, as well as learning disabilities. Deficits in visuo-spatial memory are thought to underlie some of the ... -
Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia
Kikinis, Zora; Fallon, J.H.; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; Davidson, C.; Bobrow, L.; Pelavin, P.E.; Fischl, Bruce R.; Yendiki, Anastasia; McCarley, Robert William; Kikinis, Ron; Kubicki, Marek R.; Shenton, Martha Elizabeth (Elsevier BV, 2010)The dorsolateral prefrontal cortex (DLPFC) is a brain region that has figured prominently in studies of schizophrenia and working memory, yet the exact neuroanatomical localization of this brain region remains to be defined. ... -
Reduced fractional anisotropy and axial diffusivity in white matter in 22q11.2 deletion syndrome: A pilot study
Kikinis, Zora; Asami, T.; Bouix, Sylvain; Finn, C.T.; Ballinger, T.; Tworog-Dube, E.; Kucherlapati, Raju; Kikinis, Ron; Shenton, Martha Elizabeth; Kubicki, Marek R. (Elsevier BV, 2012)Individuals with 22q11.2 deletion syndrome (22q11.2DS) evince a 30% incidence of schizophrenia. We compared the white matter (WM) of 22q11.2DS patients without schizophrenia to a group matched healthy controls using ... -
Use of Anisotropy, 3D Segmented Atlas, and Computational Analysis to Identify Gray Matter Subcortical Lesions Common to Concussive Injury from Different Sites on the Cortex
Kulkarni, Praveen; Kenkel, William; Finklestein, Seth Paul; Barchet, Thomas M.; Ren, JingMei; Davenport, Mathew; Shenton, Martha Elizabeth; Kikinis, Zora; Nedelman, Mark; Ferris, Craig F. (Public Library of Science (PLoS), 2015)Traumatic brain injury (TBI) can occur anywhere along the cortical mantel. While the cortical contusions may be random and disparate in their locations, the clinical outcomes are often similar and difficult to explain. ... -
White matter microstructural abnormalities of the cingulum bundle in youths with 22q11.2 deletion syndrome: Associations with medication, neuropsychological function, and prodromal symptoms of psychosis
Kates, Wendy R.; Olszewski, Amy K.; Gnirke, Matthew H.; Kikinis, Zora; Nelson, Joshua; Antshel, Kevin M.; Fremont, Wanda; Radoeva, Petya D.; Middleton, Frank A.; Shenton, Martha Elizabeth; Coman, Ioana L. (Elsevier BV, 2015)Background—The 22q11.2 Deletion Syndrome (22q11.2DS) is regarded as an etiologically homogenous model for understanding neuroanatomic disruptions associated with a high risk for schizophrenia. This study utilized diffusion ... -
White matter tract abnormalities between rostral middle frontal gyrus, inferior frontal gyrus and striatum in first-episode schizophrenia
Quan, Meina; Lee, Sang-Hyuk; Kubicki, Marek R.; Kikinis, Zora; Rathi, Yogesh; Seidman, Larry Joel; Mesholam-Gately, Raquelle; Goldstein, Jill M.; McCarley, Robert William; Shenton, Martha Elizabeth; Levitt, James Jonathan (Elsevier BV, 2013)Background—Previous studies have shown that frontostriatal networks, especially those involving dorsolateral prefrontal cortex (DLPFC) and ventrolateral prefrontal cortex (VLPFC) mediate cognitive functions some of which ...