Browsing by Author "Higgins, Darren"
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Identification of Listeria monocytogenes Determinants Required for Biofilm Formation
Alonso, Almaris N.; Perry, Kyle J.; Regeimbal, James M.; Regan, Patrick M.; Higgins, Darren E. (Public Library of Science, 2014)Listeria monocytogenes is a Gram-positive, food-borne pathogen of humans and animals. L. monocytogenes is considered to be a potential public health risk by the U.S. Food and Drug Administration (FDA), as this bacterium ... -
Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread
Czuczman, Mark A.; Fattouh, Ramzi; van Rijn, Jorik; Canadien, Veronica; Osborne, Suzanne; Muise, Aleixo M.; Kuchroo, Vijay K.; Higgins, Darren E.; Brumell, John H. (2014)Efferocytosis, the process by which dying/dead cells are removed by phagocytosis, plays an important role in development, tissue homeostasis and innate immunity1. Efferocytosis is mediated, in part, by receptors that bind ... -
Strain-Specific Interactions of Listeria monocytogenes with the Autophagy System in Host Cells
Cemma, Marija; Lam, Grace Y.; Stöckli, Martina; Higgins, Darren E.; Brumell, John H. (Public Library of Science, 2015)Listeria monocytogenes is an intracellular bacterial pathogen that can replicate in the cytosol of host cells. These bacteria undergo actin-based motility in the cytosol via expression of ActA, which recruits host ...