Browsing by Author "Hefti, Marco"

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    • Estrogen receptor negative/progesterone receptor positive breast cancer is not a reproducible subtype 

      Hefti, Marco M; Hu, Rong; Knoblauch, Nicholas W; Collins, Laura C; Haibe-Kains, Benjamin; Tamimi, Rulla M; Beck, Andrew H (BioMed Central, 2013)
      Introduction: Estrogen receptor (ER) and progesterone receptor (PR) testing are performed in the evaluation of breast cancer. While the clinical utility of ER as a predictive biomarker to identify patients likely to benefit ...

    • Significance Analysis of Prognostic Signatures 

      Beck, Andrew H; Knoblauch, Nicholas W.; Hefti, Marco; Kaplan, Jennifer; Schnitt, Stuart Jay; Culhane, Aedin; Schroeder, Markus S.; Risch, Thomas; Quackenbush, John; Haibe-Kains, Benjamin (Public Library of Science (PLoS), 2013)
      A major goal in translational cancer research is to identify biological signatures driving cancer progression and metastasis. A common technique applied in genomics research is to cluster patients using gene expression ...