Browsing by Author "Maliga, Zoltan"

Now showing items 1-2 of 2

    • Hydrolysis of 2′3′-cGAMP by ENPP1 and design of non-hydrolyzable analogs 

      Li, Lingyin; Yin, Qian; Kuss, Pia; Maliga, Zoltan; Millán, José L.; Wu, Hao; Mitchison, Timothy J. (2014)
      Agonists of mouse STING (TMEM173) shrink and even cure solid tumor by activating innate immunity; human STING agonists are needed to test this therapeutic hypothesis in man. The endogenous STING agonist is 2′3′-cGAMP, a ...

    • Qualifying Antibodies for Image-Based Immune Profiling and Multiplexed Tissue Imaging 

      Lin, Jia-Ren; Rashid, Rumana; Maliga, Zoltan; Izar, Benjamin; Santagata, Sandro; Du, Ziming; Wang, Shu; Aster, Jon; Songer, Peter (Springer Science and Business Media LLC, 2019-09-18)
      Multiplexed tissue imaging enables precise, spatially resolved enumeration and characterization of cell types and states in human resection specimens. A growing number of methods applicable to formalin-fixed, paraffin-embedded ...