Browsing by Author "Lebreton, Francois"
Now showing items 1-6 of 6
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Characterization of Multi-Drug Resistant Enterococcus faecalis Isolated from Cephalic Recording Chambers in Research Macaques (Macaca spp.)
Woods, Stephanie E.; Lieberman, Mia T.; Lebreton, Francois; Trowel, Elise; de la Fuente-Núñez, César; Dzink-Fox, Joanne; Fox, James G.; Gilmore, Michael S. (Public Library of Science, 2017)Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques ... -
Dual defensin strategy for targeting Enterococcus faecalis
Gilmore, Michael S.; Lebreton, Francois Herve; Van tyne, Daria Natalie (Proceedings of the National Academy of Sciences, 2013) -
Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains
Lebreton, Francois Herve; van Schaik, Willem; Manson McGuire, A.; Godfrey, P.; Griggs, A.; Mazumdar, V.; Corander, J.; Cheng, L.; Saif, S.; Young, Sarah Kerlin; Zeng, Q.; Wortman, J.; Birren, B.; Willems, R. J. L.; Earl, A. M.; Gilmore, Michael S. (American Society for Microbiology, 2013-08-30)Enterococcus faecium, natively a gut commensal organism, emerged as a leading cause of multidrug-resistant hospital-acquired infection in the 1980s. As the living record of its adaptation to changes in habitat, we sequenced ... -
Genomic transition of enterococci from gut commensals to leading causes of multidrug-resistant hospital infection in the antibiotic era
Gilmore, Michael S.; Lebreton, Francois Herve; van Schaik, Willem (Elsevier BV, 2013)The enterococci evolved over eons as highly adapted members of gastrointestinal consortia of a wide variety of hosts, but for reasons that are not entirely clear, emerged in the 1970s as leading causes of multidrug resistant ... -
Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of ?-Lactam and Vancomycin Resistance in Enterococcus faecium
García-Solache, Mónica; Lebreton, Francois Herve; McLaughlin, Robert E.; Whiteaker, James D.; Gilmore, Michael S.; Rice, Louis B. (American Society for Microbiology, 2016)The transfer of DNA between Enterococcus faecium strains has been characterized by both the movement of well-defined genetic elements and by the large-scale transfer of genomic DNA fragments. In this work we report on the ... -
Pheromone killing of multidrug-resistant Enterococcus faecalis V583 by native commensal strains
Gilmore, Michael S.; Rauch, Marcus; Ramsey, Matthew Mark; Himes, Paul R.; Varahan, Sriram; Manson, Janet M.; Lebreton, Francois Herve; Hancock, Lynn Ernest (Proceedings of the National Academy of Sciences, 2015)Multidrug-resistant Enterococcus faecalis possess numerous mobile elements that encode virulence and antibiotic resistance traits as well as new metabolic pathways, often constituting over one-quarter of the genome. It was ...