Browsing by Author "Sherman, David"

Now showing items 1-6 of 6

    • Broadening the Horizon – Level 2.5 of the HUPO-PSI Format for Molecular Interactions 

      Kerrien, Samuel; Orchard, Sandra; Montecchi-Palazzi, Luisa; Aranda, Bruno; Quinn, Antony F; Vinod, Nisha; Bader, Gary D; Xenarios, Ioannis; Wojcik, Jérôme; Tyers, Mike; Salama, John J; Ceol, Arnaud; Chatr-aryamontri, Andrew; Oesterheld, Matthias; Stümpflen, Volker; Salwinski, Lukasz; Nerothin, Jason; Cerami, Ethan; Gilson, Michael; Armstrong, John; Woollard, Peter; Hogue, Christopher; Cesareni, Gianni; Apweiler, Rolf; Hermjakob, Henning; Sherman, David Joseph; Moore, Susan; Cusick, Michael; Vidal, Marc; Eisenberg, David Miles (BioMed Central, 2007)
      Background: Molecular interaction Information is a key resource in modern biomedical research. Publicly available data have previously been provided in a broad array of diverse formats, making access to this very difficult. ...

    • Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport 

      Sherman, David Joseph; Lazarus, Michael B.; Murphy, Lea; Liu, Charles Xin; Kahne, Suzanne Walker; Ruiz, Natividad; Kahne, Daniel (Proceedings of the National Academy of Sciences, 2014)
      Gram-negative bacteria contain an unusual outer membrane that prevents the entry of most currently available antibiotics. This membrane contains a complex glycolipid, LPS, on the exterior. It is not understood how such a ...

    • Lipopolysaccharide transport to the cell surface: biosynthesis and extraction from the inner membrane 

      Simpson, Brent W.; May, Janine Margaret; Sherman, David Joseph; Kahne, Daniel; Ruiz, Natividad (The Royal Society, 2015)
      The cell surface of most Gram-negative bacteria is covered with lipopolysaccharide (LPS). The network of charges and sugars provided by the dense packing of LPS molecules in the outer leaflet of the outer membrane interferes ...

    • Lipopolysaccharide transport to the cell surface: periplasmic transport and assembly into the outer membrane 

      May, Janine Margaret; Sherman, David Joseph; Simpson, Brent W.; Ruiz, Natividad; Kahne, Daniel (The Royal Society, 2015)
      Gram-negative bacteria possess an outer membrane (OM) containing lipopolysaccharide (LPS). Proper assembly of the OM not only prevents certain antibiotics from entering the cell, but also allows others to be pumped out. ...

    • Minimum Information about a Biosynthetic Gene cluster 

      Medema, Marnix H; Kottmann, Renzo; Yilmaz, Pelin; Cummings, Matthew; Biggins, John B; Blin, Kai; de Bruijn, Irene; Chooi, Yit Heng; Claesen, Jan; Coates, R Cameron; Cruz-Morales, Pablo; Duddela, Srikanth; Düsterhus, Stephanie; Edwards, Daniel J; Fewer, David P; Garg, Neha; Geiger, Christoph; Gomez-Escribano, Juan Pablo; Greule, Anja; Hadjithomas, Michalis; Haines, Anthony S; Helfrich, Eric J N; Hillwig, Matthew L; Ishida, Keishi; Jones, Adam C; Jones, Carla S; Jungmann, Katrin; Kegler, Carsten; Kim, Hyun Uk; Kötter, Peter; Krug, Daniel; Masschelein, Joleen; Melnik, Alexey V; Mantovani, Simone M; Monroe, Emily A; Moore, Marcus; Moss, Nathan; Nützmann, Hans-Wilhelm; Pan, Guohui; Pati, Amrita; Petras, Daniel; Reen, F Jerry; Rosconi, Federico; Rui, Zhe; Tian, Zhenhua; Tobias, Nicholas J; Tsunematsu, Yuta; Wiemann, Philipp; Wyckoff, Elizabeth; Yan, Xiaohui; Yim, Grace; Yu, Fengan; Xie, Yunchang; Aigle, Bertrand; Apel, Alexander K; Balibar, Carl J; Balskus, Emily Patricia; Barona-Gómez, Francisco; Bechthold, Andreas; Bode, Helge B; Borriss, Rainer; Brady, Sean F; Brakhage, Axel A; Caffrey, Patrick; Cheng, Yi-Qiang; Clardy, Jon C.; Cox, Russell J; De Mot, René; Donadio, Stefano; Donia, Mohamed S; van der Donk, Wilfred A; Dorrestein, Pieter C; Doyle, Sean; Driessen, Arnold J M; Ehling-Schulz, Monika; Entian, Karl-Dieter; Fischbach, Michael A; Gerwick, Lena; Gerwick, William H; Gross, Harald; Gust, Bertolt; Hertweck, Christian; Höfte, Monica; Jensen, Susan E; Ju, Jianhua; Katz, Leonard; Kaysser, Leonard; Klassen, Jonathan L; Keller, Nancy P; Kormanec, Jan; Kuipers, Oscar P; Kuzuyama, Tomohisa; Kyrpides, Nikos C; Kwon, Hyung-Jin; Lautru, Sylvie; Lavigne, Rob; Lee, Chia Y; Linquan, Bai; Liu, Xinyu; Liu, Wen; Luzhetskyy, Andriy; Mahmud, Taifo; Mast, Yvonne; Méndez, Carmen; Metsä-Ketelä, Mikko; Micklefield, Jason; Mitchell, Douglas A; Moore, Bradley S; Moreira, Leonilde M; Müller, Rolf; Neilan, Brett A; Nett, Markus; Nielsen, Jens; O, Fergal; Oikawa, Hideaki; Osbourn, Anne; Osburne, Marcia S; Ostash, Bohdan; Payne, Shelley M; Pernodet, Jean-Luc; Petricek, Miroslav; Piel, Jörn; Ploux, Olivier; Raaijmakers, Jos M; Salas, José A; Schmitt, Esther K; Scott, Barry; Seipke, Ryan F; Shen, Ben; Sherman, David; Sivonen, Kaarina; Smanski, Michael J; Sosio, Margherita; Stegmann, Evi; Süssmuth, Roderich D; Tahlan, Kapil; Thomas, Christopher M; Tang, Yi; Truman, Andrew W; Viaud, Muriel; Walton, Jonathan D; Walsh, Christopher T.; Weber, Tilmann; van Wezel, Gilles P; Wilkinson, Barrie; Willey, Joanne M; Wohlleben, Wolfgang; Wright, Gerard D; Ziemert, Nadine; Zhang, Changsheng; Zotchev, Sergey B; Breitling, Rainer; Takano, Eriko; Glöckner, Frank Oliver (Springer Nature, 2015)
      A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is ...

    • Reconstitution of bacterial lipopolysaccharide transport from purified components 

      Sherman, David Joseph (2015-05-18)
      The surface of Gram-negative bacteria is largely composed of lipopolysaccharide (LPS), a complex glycolipid that contains multiple fatty acyl chains and up to hundreds of sugars. LPS is transported from its site of synthesis ...