Now showing items 1-11 of 11

    • An aptamer-functionalized chemomechanically modulated biomolecule catch-and-release system 

      Shastri, Ankita; McGregor, Lynn; Liu, Ya; Harris, Valerie; Nan, Hanqing; Mujica, Maritza; Vasquez, Yolanda; Bhattacharya, Amitabh; Ma, Yongting; Aizenberg, Michael; Kuksenok, Olga; Balazs, Anna C.; Aizenberg, Joanna; He, Ximin (Nature Publishing Group, 2015)
      The efficient extraction of (bio)molecules from fluid mixtures is vital for applications ranging from target characterization in (bio)chemistry to environmental analysis and biomedical diagnostics. Inspired by biological ...
    • A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling 

      Leslie, Daniel; Waterhouse, Anna; Berthet, Julia B; Valentin, Thomas M; Watters, Alexander; Jain, Abhishek; Kim, Philseok; Hatton, Benjamin D; Nedder, Arthur; Donovan, Kathryn; Super, Elana H; Howell, Caitlin; Johnson, Christopher P; Vu, Thy L; Bolgen, Dana; Rifai, Sami; Hansen, Anne Rosenfeld; Aizenberg, Michael; Super, Michael; Aizenberg, Joanna; Ingber, Donald Elliot (Nature Publishing Group, 2014)
      Thrombosis and biofouling of extracorporeal circuits and indwelling medical devices cause significant morbidity and mortality worldwide. We describe a bioinspired coating that repels blood from virtually any material by ...
    • Computational modeling of oscillating fins that “catch and release” targeted nanoparticles in bilayer flows 

      Liu, Ya; Bhattacharya, Amitabh; Kuksenok, Olga; He, Ximin; Aizenberg, Michael; Aizenberg, Joanna; Balazs, Anna C. (Royal Society of Chemistry (RSC), 2016)
      A number of physiological processes in living organisms involve the selective ‘‘catch and release’’ of biomolecules. Inspired by these biological processes, we use computational modeling to design synthetic systems that ...
    • Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors 

      Brudno, Yevgeny; Ennett-Shepard, Alessandra B.; Chen, Ruth R.; Aizenberg, Michael; Mooney, David J. (Elsevier BV, 2013)
    • Harnessing Cooperative Interactions between Thermoresponsive Aptamers and Gels To Trap and Release Nanoparticles 

      Liu, Ya; Kuksenok, Olga; He, Ximin; Aizenberg, Michael; Aizenberg, Joanna; Balazs, Anna C. (American Chemical Society (ACS), 2016)
      We use computational modeling to design a device that can controllably trap and release particles in solution in response to variations in temperature. The system exploits the thermo- responsive properties of end-grafted ...
    • An immobilized liquid interface prevents device associated bacterial infection in vivo 

      Chen, Jiaxuan; Howell, Caitlin; Haller, Carolyn A; Patel, Madhukar S; Ayala, Perla; Moravec, Katherine A.; Dai, Erbin; Liu, Liying; Sotiri, Irini; Aizenberg, Michael; Aizenberg, Joanna; Chaikof, Elliot L. (Elsevier BV, 2017)
      Virtually all biomaterials are susceptible to biofilm formation and, as a consequence, device-associated infection. The concept of an immobilized liquid surface, termed slippery liquid-infused porous surfaces (SLIPS), ...
    • In Vivo Targeting through Click Chemistry 

      Brudno, Yevgeny; Desai, Rajiv; Kwee, Brian Joseph; Joshi, Neel S.; Aizenberg, Michael; Mooney, David J. (Wiley-Blackwell, 2015)
      Targeting small molecules to diseased tissues as therapy or diagnosis is a significant challenge in drug delivery. Drug-eluting devices implanted during invasive surgery allow the controlled presentation of drugs at the ...
    • Inverting the Swelling Trends in Modular Self-Oscillating Gels Crosslinked by Redox-Active Metal Bipyridine Complexes 

      Aizenberg, Michael; Okeyoshi, Kosuke; Aizenberg, Joanna (Wiley, 2017)
      The developing field of active, stimuli-responsive materials is in need for new dynamic architectures that may offer unprecedented chemomechanical switching mechanisms. Towards this goal, syntheses of polymerizable bipyridine ...
    • New Architectures for Designed Catalysts: Selective Oxidation using AgAu Nanoparticles on Colloid-Templated Silica 

      Shirman, Tanya; Lattimer, Judith; Luneau, Mathilde; Shirman, Elijah; Reece, Christian; Aizenberg, Michael; Madix, Robert James; Aizenberg, Joanna; Friend, Cynthia M. (Wiley, 2017)
      A highly modular synthesis of designed catalysts with controlled bimetallic nanoparticle size and composition and a well-defined structural hierarchy is demonstrated. Exemplary catalysts—bimetallic dilute Ag-in-Au nanoparticles ...
    • Stability of Surface-Immobilized Lubricant Interfaces under Flow 

      Howell, Caitlin; Vu, Thy L.; Johnson, Christopher; Hou, Xu; Ahanotu, Onyemaechi; Alvarenga, Jack; Leslie, Daniel; Uzun, Oktay; Waterhouse, Anna; Kim, Philseok; Super, Michael; Aizenberg, Michael; Ingber, Donald Elliot; Aizenberg, Joanna (American Chemical Society (ACS), 2015)
      The stability and longevity of surface-stabilized lubricant layers is a critical question in their application as low- and nonfouling slippery surface treatments in both industry and medicine. Here, we investigate lubricant ...
    • Synthetic homeostatic materials with chemo-mechano-chemical self-regulation 

      He, Ximin; Aizenberg, Michael; Kuksenok, Olga; Zarzar, Lauren D.; Shastri, Ankita; Balazs, Anna C.; Aizenberg, Joanna (Springer Nature, 2012)
      Living organisms have unique homeostatic abilities, maintaining tight control of their local environment through interconversions of chemical and mechanical energy and self-regulating feedback loops organized hierarchically ...