Now showing items 1-14 of 14

    • Acute Histologic Chorioamnionitis at Term: Nearly Always Noninfectious 

      Roberts, Drucilla Jane; Celi, Ann Catherine; Riley, Laura E.; Onderdonk, Andrew Bruce; Boyd, Theonia Kamman; Johnson, Lise Carolyn; Lieberman, Ellice S. (Public Library of Science, 2012)
      Background: The link between histologic acute chorioamnionitis and infection is well established in preterm deliveries, but less well-studied in term pregnancies, where infection is much less common. Methodology/Principal ...
    • Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes 

      Veiga, Patrick; Gallini, Carey Ann; Beal, C.; Michaud, Monia; Delaney, Mary Louise Rodriguez; DuBois, A.; Khlebnikov, A.; van Hylckama Vlieg, J. E. T.; Punit, S.; Glickman, Jonathan Neil; Onderdonk, Andrew Bruce; Glimcher, Laurie Hollis; Garrett, Wendy S. (Proceedings of the National Academy of Sciences, 2010)
      Intestinal health requires the coexistence of eukaryotic self with the gut microbiota and dysregulated host-microbial interactions can result in intestinal inflammation. Here, we show that colitis improved in T-bet(-/-)Rag2(-/-) ...
    • Diversity of the Gut Microbiota and Eczema in Early Life 

      Forno, Erick; Onderdonk, Andrew Bruce; McCracken, John Patrick; Litonjua, Augusto Ampil; Laskey, Daniel; Delaney, Mary Louise Rodriguez; DuBois, Andrea M; Gold, Diane R.; Ryan, Louise Marie; Weiss, Scott Tillman; Celedón, Juan C (BioMed Central, 2008)
      Background: A modest number of prospective studies of the composition of the intestinal microbiota and eczema in early life have yielded conflicting results. Objective: To examine the relationship between the bacterial ...
    • Does the Computerized Display of Charges Affect Inpatient Ancillary Test Utilization? 

      Bates, David; Kuperman, Gilad J.; Jha, Ashish; Teich, Jonathan; Orav, Endel; Ma'luf, Nell; Onderdonk, Andrew; Pugatch, Robert; Wybenga, Donald; Winkelman, James; Brennan, Troyen; Komaroff, Anthony; Tanasijevic, Milenko (American Medical Association (AMA), 1997-11-24)
      Background: The computerized display of charges for ancillary tests in outpatients has been found to affect physician-ordering behavior, but this issue has not been studied in inpatients. Objective: To assess whether ...
    • Dynamics of the Microbiota in Response to Host Infection 

      Belzer, Clara; Gerber, Georg K.; Roeselers, Guus; Delaney, Mary; DuBois, Andrea; Liu, Qing; Belavusava, Vera; Yeliseyev, Vladimir; Houseman, Andres; Onderdonk, Andrew; Cavanaugh, Colleen; Bry, Lynn (Public Library of Science, 2014)
      Longitudinal studies of the microbiota are important for discovering changes in microbial communities that affect the host. The complexity of these ecosystems requires rigorous integrated experimental and computational ...
    • Enhanced Susceptibility to Infections in a Diabetic Wound Healing Model 

      Hirsch, Tobias; Spielmann, Malte; Zuhaili, Baraa; Koehler, Till; Fossum, Magdalena; Steinau, Hans-Ulrich; Yao, Feng; Steinstraesser, Lars; Onderdonk, Andrew Bruce; Eriksson, Elof (BioMed Central, 2008)
      Background: Wound infection is a common complication in diabetic patients. The progressive spread of infections and development of drug-resistant strains underline the need for further insights into bacterial behavior in ...
    • Genomically Informed Surveillance for Carbapenem-Resistant Enterobacteriaceae in a Health Care System 

      Pecora, Nicole D.; Li, Ning; Allard, Marc; Li, Cong; Albano, Esperanza; Delaney, Mary; Dubois, Andrea; Onderdonk, Andrew B.; Bry, Lynn (American Society of Microbiology, 2015)
      ABSTRACT Carbapenem-resistant Enterobacteriaceae (CRE) are an urgent public health concern. Rapid identification of the resistance genes, their mobilization capacity, and strains carrying them is essential to direct hospital ...
    • Inferring Dynamic Signatures of Microbes in Complex Host Ecosystems 

      Gerber, Georg Kurt; Onderdonk, Andrew Bruce; Bry, Lynn (Public Library of Science, 2012)
      The human gut microbiota comprise a complex and dynamic ecosystem that profoundly affects host development and physiology. Standard approaches for analyzing time-series data of the microbiota involve computation of measures ...
    • Maternal intestinal flora and wheeze in early childhood 

      Lange, Nancy; Celedón, Juan C.; Forno, Erick; Ly, Ngoc P.; Onderdonk, Andrew Bruce; Bry, Lynn; Delaney, Mary Louise Rodriguez; DuBois, Andrea M.; Gold, Diane R.; Weiss, Scott Tillman; Litonjua, Augusto Ampil (Wiley-Blackwell, 2011)
      Background: Increasing evidence links altered intestinal flora in infancy to eczema and asthma. No studies have investigated the influence of maternal intestinal flora on wheezing and eczema in early childhood. Objective: To ...
    • Mode of Delivery and Cord Blood Cytokines: A Birth Cohort Study 

      Ly, Ngoc P; Ruiz-Pérez, Begoña; Tzianabos, Arthur O; Liang, Catherine; Laskey, Daniel; DuBois, Andrea M; Levy, Hara; Celedón, Juan C; Onderdonk, Andrew Bruce; Litonjua, Augusto Ampil; Delaney, Mary Louise Rodriguez; Gold, Diane R.; Ryan, Louise Marie; Weiss, Scott Tillman (BioMed Central, 2006)
      Background: The mechanisms for the association between birth by cesarean section and atopy and asthma are largely unknown. Objective: To examine whether cesarean section results in neonatal secretion of cytokines that are ...
    • Persistence Survey of Toxic Shock Syndrome Toxin-1 Producing Staphylococcus Aureus and Serum Antibodies to this Superantigen in Five Groups of Menstruating Women 

      Parsonnet, Jeffrey; Hansmann, Melanie A.; Seymour, Jon L.; Delaney, Mary Louise Rodriguez; DuBois, Andrea M.; Modern, Paul A.; Jones, Michaelle B.; Wild, John E.; Onderdonk, Andrew Bruce (BioMed Central, 2010)
      Background: Menstrual Toxic Shock Syndrome (mTSS) is thought to be associated with the vaginal colonization with specific strains of Staphylococcus aureus TSST-1 in women who lack sufficient antibody titers to this toxin. ...
    • Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients 

      Reddy, Krishna P.; Bajwa, Ednan K.; Parker, Robert A.; Onderdonk, Andrew B.; Walensky, Rochelle P. (Oxford University Press, 2016)
      Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This ...
    • Subacute Bacterial Endocarditis with Leptotrichia goodfellowii in a Patient with a Valvular Allograft: A Case Report and Review of the Literature 

      Matias, Wilfredo R.; Bourque, Daniel L.; Niwano, Tomoko; Onderdonk, Andrew B.; Katz, Joel T. (Hindawi Publishing Corporation, 2016)
      Leptotrichia species are normal constituents of the oral cavity and the genitourinary tract microbiota that are known to provoke disease in immunocompromised patients and rarely in immunocompetent individuals. Following ...
    • The Villain Team-Up or how Trichomonas vaginalis and bacterial vaginosis alter innate immunity in concert 

      Fichorova, Raina N; Buck, Olivia R; Yamamoto, Hidemi S; Fashemi, Titilayo; Dawood, Hassan Y; Fashemi, Bisiayo; Hayes, Gary R; Beach, David H; Takagi, Yuko; Delaney, Mary L; Nibert, Max L; Singh, Bibhuti N; Onderdonk, Andrew B (BMJ Publishing Group, 2013)
      Objectives: Complex interactions of vaginal microorganisms with the genital tract epithelium shape mucosal innate immunity, which holds the key to sexual and reproductive health. Bacterial vaginosis (BV), a microbiome-disturbance ...