Now showing items 1-20 of 68

    • Aberrant semantic activation in schizophrenia: a neurophysiological study 

      Nestor, PG; Kimble, MO; O'Donnell, BF; Smith, L; Niznikiewicz, Margaret A.; Shenton, Martha Elizabeth; McCarley, RW (American Psychiatric Publishing, 1997)
      OBJECTIVE: Schizophrenia has long been thought to be characterized by a fundamental disturbance in semantic associations, which has often been presumed to be of neurobiological origin. The authors examined the neurophysiological ...
    • Abnormal Angular Gyrus Asymmetry in Schizophrenia 

      Niznikiewicz, Margaret A.; Donnino, Robert; McCarley, Robert William; Nestor, Paul Gerard; Iosifescu, Daniel V.; O'Donnell, Brian; Levitt, James Jonathan; Shenton, Martha Elizabeth (American Psychiatric Publishing, 2000)
      Objective: Few studies have evaluated the parietal lobe in schizophrenia despite the fact that it has an important role in attention, memory, and language—all functions that have been reported to be abnormal in schizophrenia. ...
    • Abnormal Neural Synchrony in Schizophrenia 

      Spencer, Kevin M.; Nestor, Paul Gerard; Niznikiewicz, Margaret A.; Salisbury, Dean F.; Shenton, Martha Elizabeth; McCarley, Robert William (2003)
      Schizophrenia has been conceptualized as a failure of cognitive integration, and abnormalities in neural circuitry (particularly inhibitory interneurons) have been proposed as a basis for this disorder. We used measures ...
    • Abnormal pitch mismatch negativity in individuals with schizotypal personality disorder 

      Niznikiewicz, Margaret A.; Spencer, Kevin M.; Dickey, Chandlee C.; Voglmaier, Martina M.; Seidman, Larry Joel; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2009)
      Background: The goal of the study was to examine mismatch negativity (MMN) in schizotypal personality disorder (SPD) individuals. Abnormal MMN has been a consistent finding in chronic schizophrenia and there are also have ...
    • Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia 

      Asami, Takeshi; Saito, Yukiko; Whitford, Thomas; Makris, Nikos; Niznikiewicz, Margaret A.; McCarley, Robert William; Shenton, Martha Elizabeth; Kubicki, Marek R. (Elsevier BV, 2013)
      Introduction—The Middle Longitudinal Fascicle (MdLF) is a long association fiber connecting the superior temporal gyrus (STG) and temporal pole with the angular gyrus through the white matter of the STG, structures which ...
    • Altered orbitofrontal sulcogyral pattern in schizophrenia 

      Nakamura, M.; Nestor, Paul Gerard; McCarley, Robert William; Levitt, James Jonathan; Hsu, Liangge; Kawashima, T.; Niznikiewicz, Margaret A.; Shenton, Martha Elizabeth (Oxford University Press (OUP), 2007)
      Orbitofrontal alteration in schizophrenia has not been well characterized, likely due to marked anatomical variability. To investigate the presence of such alterations, we evaluated the sulcogyral pattern of this ‘H-shaped’ ...
    • Anterior limb of the internal capsule in schizophrenia: a diffusion tensor tractography study 

      Rosenberger, Gudrun; Nestor, Paul Gerard; Oh, Jungsu S.; Levitt, James Jonathan; Kindleman, Gordon; Bouix, Sylvain; Fitzsimmons, Jennifer J; Niznikiewicz, Margaret A.; Westin, Carl-Fredrik; Kikinis, Ron; McCarley, Robert William; Shenton, Martha Elizabeth; Kubicki, Marek R. (Springer Science + Business Media, 2012)
      Thalamo-cortical feedback loops play a key role in the processing and coordination of processing and integration of perceptual inputs and outputs, and disruption in this connection has long been hypothesized to contribute ...
    • Association Between Reduced Extraversion and Right Posterior Fusiform Gyrus Gray Matter Reduction in Chronic Schizophrenia 

      Onitsuka, Toshiaki; Nestor, Paul Gerard; Gurrera, Ronald Joseph; Shenton, Martha Elizabeth; Kasai, Kiyoto; Frumin, Melissa; Niznikiewicz, Margaret A.; McCarley, Robert William (American Psychiatric Publishing, 2005)
      Objective: The authors examined the association between volume of the fusiform gyrus, a region involved in face processing, and the personality trait of extraversion in patients with schizophrenia. Method: Male patients ...
    • Associative memory in chronic schizophrenia: a computational model 

      Han, S Duke; Nestor, Paul Gerard; Shenton, Martha Elizabeth; Niznikiewicz, Margaret A.; Hannah, Gordon; McCarley, Robert William (Elsevier BV, 2003)
      We developed a computer model to simulate associative memory recall of patients with chronic schizophrenia. Model inputs consisted of words derived from normative data that differed in terms of connectivity and network ...
    • Attentional Control and Intelligence: MRI Orbital Frontal Gray Matter and Neuropsychological Correlates 

      Nestor, Paul G.; Nakamura, Motoaki; Niznikiewicz, Margaret; Levitt, James J.; Newell, Dominick T.; Shenton, Martha E.; McCarley, Robert W. (Hindawi Publishing Corporation, 2015)
      Attentional control is a key function of working memory that is hypothesized to play an important role in psychometric intelligence. To test the neuropsychological underpinnings of this hypothesis, we examined full-scale ...
    • Attentional networks and cingulum bundle in chronic schizophrenia? 

      Nestor, Paul Gerard; Kubicki, Marek R.; Spencer, Kevin M.; Niznikiewicz, Margaret A.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2007)
      Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n=18) also had available magnetic resonance diffusion tensor imaging (DTI) ...
    • Auditory processing abnormalities in schizotypal personality disorder: An fMRI experiment using tones of deviant pitch and duration 

      Dickey, Chandlee C.; Morocz, Istvan; Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Toner, Sarah; Khan, Usman; Dreusicke, Mark; Yoo, Seung-Schik; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2008)
      Background: One of the cardinal features of schizotypal personality disorder (SPD) is language abnormalities. The focus of this study was to determine whether or not there are also processing abnormalities of pure tones ...
    • The building blocks of social communication 

      Niznikiewicz, Margaret A. (University of Finance and Management in Warsaw, 2013)
      In the present review, social communication will be discussed in the context of social cognition, and cold and hot cognition. The review presents research on prosody, processing of faces, multimodal processing of voice and ...
    • Cerebral white matter abnormalities and their associations with negative but not positive symptoms of schizophrenia 

      Asami, Takeshi; Hyuk Lee, Sang; Bouix, Sylvain; Rathi, Yogesh; Whitford, Thomas; Niznikiewicz, Margaret A.; Nestor, Paul Gerard; McCarley, Robert William; Shenton, Martha Elizabeth; Kubicki, Marek R. (Elsevier BV, 2014)
      Although diffusion tensor imaging (DTI) studies have reported fractional anisotropy (FA) abnormalities in multiple white matter (WM) regions in schizophrenia, relationship between abnormal FA and negative symptoms has not ...
    • Clinical high risk and first episode schizophrenia: Auditory event-related potentials 

      Del Re, Elisabetta; Spencer, Kevin M.; Oribe, Naoya; Mesholam-Gately, Raquelle; Goldstein, Jill M.; Shenton, Martha Elizabeth; Petryshen, Tracey Lynn; Seidman, Larry Joel; McCarley, Robert William; Niznikiewicz, Margaret A. (Elsevier BV, 2015)
      The clinical high risk (CHR) period is a phase denoting a risk for overt psychosis during which subacute symptoms often appear, and cognitive functions may deteriorate. To compare biological indices during this phase with ...
    • Clinical, cognitive, and social characteristics of a sample of neuroleptic-naive persons with schizotypal personality disorder 

      Dickey, Chandlee C.; McCarley, Robert William; Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Seidman, Larry Joel; Kim, Sunnie; Shenton, Martha Elizabeth (Elsevier BV, 2005)
      Introduction: Schizotypal personality disorder (SPD) shares with schizophrenia many biological features, yet little is known about the clinical characteristics of persons diagnosed with this disorder. This report describes ...
    • Cognitive dysfunction in schizophrenia: unifying basic research and clinical aspects 

      McCarley, Robert William; Niznikiewicz, Margaret A.; Salisbury, Dean F.; Nestor, Paul Gerard; O’Donnell, Brian F.; Hirayasu, Yoshio; Grunze, Heinz; Greene, Robert W.; Shenton, Martha Elizabeth (Springer Science + Business Media, 1999)
      Seeking to unite psychological and biological approaches, this paper links cognitive and cellular hypotheses and data about thought and language abnormalities in schizophrenia. The common thread, it is proposed, is a ...
    • A comparative profile analysis of neuropsychological function in men and women with schizotypal personality disorder 

      Voglmaier, Martina M.; Seidman, Larry Joel; Niznikiewicz, Margaret A.; Dickey, Chandlee C.; Shenton, Martha Elizabeth; McCarley, Robert William (Elsevier BV, 2005)
      The purpose of this study was to compare the cognitive profiles of men and women with clinically defined schizotypal personality disorder (SPD). We examined the neuropsychological profile of SPD in 26 right-handed females ...
    • Comparing prefrontal gray and white matter contributions to intelligence and decision making in schizophrenia and healthy controls. 

      Nestor, Paul Gerard; Kubicki, Marek R.; Nakamura, Motoaki; Niznikiewicz, Margaret A.; McCarley, Robert William; Shenton, Martha Elizabeth (American Psychological Association (APA), 2010)
      We examined the relationship between neuropsychological performance and magnetic resonance imaging (MRI) of the orbital frontal cortex (OFC) and diffusion tensor imaging (DTI) of the cingulum bundle (CB) within groups of ...
    • Corpus Callosum Abnormalities and Their Association with Psychotic Symptoms in Patients with Schizophrenia 

      Whitford, Thomas; Kubicki, Marek R.; Schneiderman, Jason S.; O, Lauren J.; King, Rebecca; Alvarado, Jorge L.; Khan, Usman; Markant, Douglas; Nestor, Paul Gerard; Niznikiewicz, Margaret A.; McCarley, Robert William; Westin, Carl-Fredrik; Shenton, Martha Elizabeth (Elsevier BV, 2010)
      Background—Whilst the neuroanatomical underpinnings of the functional brain disconnectivity observed in patients with schizophrenia remain elusive, white matter fiber bundles of the brain are a likely candidate given that ...