Now showing items 1-2 of 2

    • Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins 

      Cho, JinAh; Chinnapen, Daniel Jean-Francois; Aamar, Emil; te Welscher, Yvonne Maria; Lencer, Wayne Isaac; Massol, Ramiro (Frontiers Media S.A., 2012)
      Some bacterial toxins and viruses have evolved the capacity to bind mammalian glycosphingolipids to gain access to the cell interior, where they can co-opt the endogenous mechanisms of cellular trafficking and protein ...
    • TorsinA participates in endoplasmic reticulum-associated degradation 

      Nery, Flávia C.; Armata, Ioanna A.; Farley, Jonathan E.; Cho, JinAh; Yaqub, Uzma; Chen, Pan; da Hora, Cintia Carla; Wang, Qiuyan; Tagaya, Mitsuo; Klein, Christine; Tannous, Bakhos A.; Caldwell, Kim A.; Caldwell, Guy A.; Lencer, Wayne I.; Ye, Yihong; Breakefield, Xandra Owens (Nature Publishing Group, 2012)
      TorsinA is an \(AAA^+\) ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function for torsinA in ...