Browsing by Author "Beyer, Elsa Margaret"

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    • Linear combinations of docking affinities explain quantitative differences in RTK signaling 

      Gordus, Andrew; Krall, Jordan A; Kaushansky, Alexis; Wolf-Yadlin, Alejandro; Sevecka, Mark; Chang, Bryan H; Rush, John; Beyer, Elsa Margaret; Macbeath, Gavin (Nature Publishing Group, 2009)
      Receptor tyrosine kinases (RTKs) process extracellular cues by activating a broad array of signaling proteins. Paradoxically, they often use the same proteins to elicit diverse and even opposing phenotypic responses. Binary, ...