Browsing by Author "Chen, Chiao-Lin"
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The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming
Tang, Hong-Wen; Hu, Yanhui; Chen, Chiao-Lin; Xia, Baolong; Zirin, Jonathan; Yuan, Min; Asara, John; Rabinow, Leonard; Perrimon, Norbert (Elsevier BV, 2018-05-01)Nutrient deprivation induces autophagy through inhibiting TORC1 activity. We describe a novel mechanism in Drosophila by which TORC1 regulates RNA processing of Atg transcripts and alters ATG protein levels and activities ...