Browsing by Author "Rifai, Nader"
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Apolipoprotein(a) Size and Lipoprotein(a) Concentration and Future Risk of Angina Pectoris with Evidence of Severe Coronary Atherosclerosis in Men: The Physicians' Health Study
Rifai, Nader; Ma, Jing; Sacks, Frank Martin; Ridker, Paul M.; Hernandez, W; Stampfer, Meir; Marcovina, S (American Association for Clinical Chemistry (AACC), 2004)The relationship of lipoprotein (a) [Lp(a)] concentrations with risk of coronary heart disease needs clarification, especially for threshold values for increased risk and for possible interactions with LDL-cholesterol ... -
Circulating Levels of Resistin and Risk of Type 2 Diabetes in Men and Women: Results from Two Prospective Cohorts
Chen, Brian H.; Song, Yiqing; Ding, Eric L.; Roberts, Christian K.; Manson, JoAnn Elisabeth; Rifai, Nader; Buring, Julie Elizabeth; Gaziano, John Michael; Liu, Simin (American Diabetes Association, 2009)OBJECTIVE—The purpose of this study was to investigate the role of circulating resistin levels in the development of type 2 diabetes using two prospective cohorts of well-characterized men and women. RESEARCH DESIGN AND ... -
Effects of Vitamin D Supplementation on C-peptide and 25-hydroxyvitamin D Concentrations at 3 and 6 Months
Chandler, Paulette D.; Giovannucci, Edward L.; Scott, Jamil B.; Bennett, Gary G.; Ng, Kimmie; Chan, Andrew T.; Hollis, Bruce W.; Rifai, Nader; Emmons, Karen M.; Fuchs, Charles S.; Drake, Bettina F. (Nature Publishing Group, 2015)The link between African-Americans’ disproportionate rates of diabetes, obesity and vitamin D deficiency may be marked by C-peptide as an indicator of insulin secretion. We hypothesize that vitamin D supplementation will ... -
Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study
Kinlay, Scott; Schwartz, Gregory Richard; Olsson, Anders G.; Rifai, Nader; Bao, Weihang; Libby, Peter; Ganz, Peter (Elsevier BV, 2009)Objective To examine the relationship of baseline tissue plasminogen activator (t-PA) to early cardiovascular risk after an acute coronary syndrome, and the effect of intensive statin therapy. Methods We measured ... -
Inflammatory Biomarkers, Death, and Recurrent Nonfatal Coronary Events after an Acute Coronary Syndrome in the MIRACL Study
Zamani, Payman; Schwartz, Gregory G.; Olsson, Anders G.; Rifai, Nader; Bao, Weihang; Libby, Peter; Ganz, Peter; Kinlay, Scott (Blackwell Publishing, 2013)Background: In acute coronary syndromes, C‐reactive protein (CRP) strongly relates to subsequent death, but surprisingly not to recurrent myocardial infarction. Other biomarkers may reflect different processes related to ... -
Interleukin-6 Receptor Gene, Plasma C-Reactive Protein, and Diabetes Risk in Women
Qi, Lu; Rifai, Nader; Hu, Frank B. (American Diabetes Association, 2009)OBJECTIVE—Recent genome-wide association studies (GWASs) related common variants in the interleukin-6 (Il-6) receptor (IL6R) gene to plasma C-reactive protein (CRP) concentrations. Because IL6R variants were previously ... -
Interrelationship of Multiple Endothelial Dysfunction Biomarkers with Chronic Kidney Disease
Chen, Jing; Hamm, L. Lee; Mohler, Emile R.; Hudaihed, Alhakam; Arora, Robin; Chen, Chung-Shiuan; Liu, Yanxi; Browne, Grace; Mills, Katherine T.; Kleinpeter, Myra A.; Simon, Eric E.; Rifai, Nader; Klag, Michael J.; He, Jiang (Public Library of Science, 2015)The interrelationship of multiple endothelial biomarkers and chronic kidney disease (CKD) has not been well studied. We measured asymmetric dimethylarginine (ADMA), L-arginine, soluble intercellular adhesion molecule-1 ... -
Novel Association of ABO Histo-blood Group Antigen with Soluble ICAM-1: Results of a Genome-wide Association Study of 6,578 Women
Paré, Guillaume; Kellogg, Mark; Badola, Sunita; Miletich, Joseph P.; Gibson, Greg; Chasman, Daniel Ian; Zee, Robert Yuk Lung; Rifai, Nader; Ridker, Paul M. (Public Library of Science, 2008)While circulating levels of soluble Intercellular Adhesion Molecule 1 (sICAM-1) have been associated with diverse conditions including myocardial infarction, stroke, malaria, and diabetes, comprehensive analysis of the ... -
Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study
Zamani, Payman; Ganz, Peter; Libby, Peter; Sutradhar, Santosh C.; Rifai, Nader; Nicholls, Stephen J.; Nissen, Steven E.; Kinlay, Scott (Elsevier BV, 2012)Background Antihypertensive agents lower the risk of cardiovascular events, but whether they affect pathways important in inflammation and plaque remodeling in atherosclerosis is uncertain. We assessed whether 2 commonly ... -
STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies
Bossuyt, Patrick M; Reitsma, Johannes B; Bruns, David E; Gatsonis, Constantine A; Glasziou, Paul P; Irwig, Les; Lijmer, Jeroen G; Moher, David; Rennie, Drummond; de Vet, Henrica C W; Kressel, Herbert Y; Rifai, Nader; Golub, Robert M; Altman, Douglas G; Hooft, Lotty; Korevaar, Daniël A; Cohen, Jérémie F (BMJ Publishing Group Ltd., 2015)Incomplete reporting has been identified as a major source of avoidable waste in biomedical research. Essential information is often not provided in study reports, impeding the identification, critical appraisal, and ...