Now showing items 1-2 of 2

    • PPARγ is a Major Driver of the Accumulation and Phenotype of Adipose-Tissue \(T_{reg}\) Cells 

      Cipolletta, Daniela; Feuerer, Markus; Li, Amy; Kamei, Nozomu; Lee, Jongsoon; Shoelson, Steven E.; Benoist, Christophe O.; Mathis, Diane J. (Nature Publishing Group, 2012)
      Obesity and type-2 diabetes have increased markedly over the past few decades, in parallel. One of the major links between these two disorders is chronic, low-grade inflammation. Prolonged nutrient excess promotes the ...
    • Regulation of Diet-Induced Adipose Tissue and Systemic Inflammation by Salicylates and Pioglitazone 

      Kim, Myung-Sunny; Yamamoto, Yasuhiko; Kim, Kyungjin; Kamei, Nozomu; Shimada, Takeshi; Liu, Libin; Moore, Kristin; Woo, Ju Rang; Shoelson, Steven E.; Lee, Jongsoon (Public Library of Science, 2013)
      It is increasingly accepted that chronic inflammation participates in obesity-induced insulin resistance and type 2 diabetes (T2D). Salicylates and thiazolidinediones (TZDs) both have anti-inflammatory and anti-hyperglycemic ...