Now showing items 1-5 of 5

    • Altered expression of norepinephrine transporter and norepinephrine in human placenta cause pre-eclampsia through regulated trophoblast invasion 

      Na, Kyu-Hwan; Choi, Jong Ho; Kim, Chun-Hyung; Kim, Kwang-Soo; Kim, Gi Jin (The Korean Society for Reproductive Medicine, 2013)
      Objective: We investigated the norepinephrine transporter (NET) expression in normal and pre-eclamptic placentas and analyzed the invasion activity of trophoblastic cells based on norepinephrine (NE)-NET regulation. Methods: ...
    • Direct Reprogramming of Rat Neural Precursor Cells and Fibroblasts into Pluripotent Stem Cells 

      Kang, Hoon-Chul; Yang, Eungi; Park, Kyung-Soon; Lee, Kyung-Ah; Hwang, Dong-Youn; Lanza, Robert; Reh, Thomas A.; Chang, Mi-Yoon; Kim, Chun-Hyung; Kim, Dohoon; Moon, Jung-Il; Ko, Sanghyeok; Park, Junpil; Chung, Young; Kim, Kwang-Soo (Public Library of Science, 2010)
      Background: Given the usefulness of rats as an experimental system, an efficient method for generating rat induced pluripotent stem (iPS) cells would provide researchers with a powerful tool for studying human physiology ...
    • The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity 

      Jung, Hoe-Yune; Kim, Yu-Hee; Kim, In-Bo; Jeong, Ju Seong; Lee, Jung-Han; Do, Myoung-Sool; Jung, Seung-Pil; Kim, Kwang-Soo; Kim, Kyong-Tai; Kim, Jong-Bae (Hindawi Publishing Corporation, 2013)
      This study investigates the inhibitory effects of Korean mistletoe extract (KME) on adipogenic factors in 3T3-L1 cells and obesity and nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet. Male C57Bl/6 mice ...
    • The RAB39B p.G192R mutation causes X-linked dominant Parkinson’s disease 

      Mata, Ignacio F.; Jang, Yongwoo; Kim, Chun-Hyung; Hanna, David S.; Dorschner, Michael O.; Samii, Ali; Agarwal, Pinky; Roberts, John W.; Klepitskaya, Olga; Shprecher, David R.; Chung, Kathryn A.; Factor, Stewart A.; Espay, Alberto J.; Revilla, Fredy J.; Higgins, Donald S.; Litvan, Irene; Leverenz, James B.; Yearout, Dora; Inca-Martinez, Miguel; Martinez, Erica; Thompson, Tiffany R.; Cholerton, Brenna A.; Hu, Shu-Ching; Edwards, Karen L.; Kim, Kwang-Soo; Zabetian, Cyrus P. (BioMed Central, 2015)
      Objective: To identify the causal gene in a multi-incident U.S. kindred with Parkinson’s disease (PD). Methods: We characterized a family with a classical PD phenotype in which 7 individuals (5 males and 2 females) were ...
    • Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells 

      Feng, Qiang; Shabrani, Namrata; Thon, Jonathan N.; Huo, Hongguang; Thiel, Austin; Machlus, Kellie R.; Kim, Kyungho; Brooks, Julie; Li, Feng; Luo, Chenmei; Kimbrel, Erin A.; Wang, Jiwu; Kim, Kwang-Soo; Italiano, Joseph; Cho, Jaehyung; Lu, Shi-Jiang; Lanza, Robert (Elsevier, 2014)
      Summary Human induced pluripotent stem cells (iPSCs) provide a potentially replenishable source for the production of transfusable platelets. Here, we describe a method to generate megakaryocytes (MKs) and functional ...