Browsing by Author "Martin, Constance"

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    • Efferocytosis is an Innate Antibacterial Mechanism of Mycobacterium tuberculosis Control 

      Martin, Constance Jean (2012-12-13)
      One third of the world’s population is infected with Mycobacterium tuberculosis, causing two million deaths annually. The bacteria avoid immune clearance by persisting within macrophages by subverting normal phagosome ...

    • Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection 

      Nunes-Alves, Cláudio; Booty, Matthew G.; Carpenter, Stephen M.; Rothchild, Alissa C.; Martin, Constance J.; Desjardins, Danielle; Steblenko, Katherine; Kløverpris, Henrik N.; Madansein, Rajhmun; Ramsuran, Duran; Leslie, Alasdair; Correia-Neves, Margarida; Behar, Samuel M. (Public Library of Science, 2015)
      The immune system can recognize virtually any antigen, yet T cell responses against several pathogens, including Mycobacterium tuberculosis, are restricted to a limited number of immunodominant epitopes. The host factors ...