Browsing by Author "Zhang, Xuehong"

Now showing items 1-6 of 6

    • Association between Cutaneous Nevi and Breast Cancer in the Nurses' Health Study: A Prospective Cohort Study 

      Zhang, Mingfeng; Zhang, Xuehong; Qureshi, Abrar A.; Eliassen, A. Heather; Hankinson, Susan E.; Han, Jiali (Public Library of Science, 2014)
      Background: Cutaneous nevi are suggested to be hormone-related. We hypothesized that the number of cutaneous nevi might be a phenotypic marker of plasma hormone levels and predict subsequent breast cancer risk. Methods and ...

    • Blood Donation and Colorectal Cancer Incidence and Mortality in Men 

      Zhang, Xuehong; Ma, Jing; Wu, Kana; Chan, Andrew Tan; Fuchs, Charles Stewart; Giovannucci, Edward L. (Public Library of Science, 2012)
      Background: Although blood donations may reduce body iron stores, to date, prospective data on frequent blood donation and colorectal cancer risk are limited. Methodology/Principal Findings: We tested whether frequent ...

    • Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis 

      Kim, Sun A; Inamura, Kentaro; Yamauchi, Mai; Nishihara, Reiko; Mima, Kosuke; Sukawa, Yasutaka; Li, Tingting; Yasunari, Mika; Morikawa, Teppei; Fitzgerald, Kathryn C; Fuchs, Charles S; Wu, Kana; Chan, Andrew T; Zhang, Xuehong; Ogino, Shuji; Qian, Zhi Rong (Nature Publishing Group, 2016)
      Background: Loss of CDH1 (E-cadherin) expression in cancer cells may promote cell migration and invasion. Therefore, we hypothesised that loss of CDH1 expression in colorectal carcinoma might be associated with aggressive ...

    • Oral Contraceptive Use and Colorectal Cancer in the Nurses' Health Study I and II 

      Charlton, Brittany Michelle; Wu, Kana; Zhang, Xuehong; Giovannucci, Edward L.; Fuchs, Charles Stewart; Missmer, Stacey Ann; Rosner, Bernard Alfred; Hankinson, Susan Elizabeth; Willett, Walter C.; Michels, Karin B. (American Association for Cancer Research (AACR), 2015)
      Background—It remains unclear if oral contraceptive (OC) use is associated with the incidence of colorectal cancer. Few studies have examined this association by duration of OC use, time since last OC use, and different ...

    • A Prospective Analysis of Meat Mutagens and Colorectal Cancer in the Nurses’ Health Study and Health Professionals Follow-up Study 

      Le, Ngoan Tran; Michels, Fernanda Alessandra Silva; Song, Mingyang; Zhang, Xuehong; Bernstein, Adam M.; Giovannucci, Edward L.; Fuchs, Charles S.; Ogino, Shuji; Chan, Andrew T.; Sinha, Rashmi; Willett, Walter C.; Wu, Kana (National Institute of Environmental Health Sciences, 2016)
      Background: Heterocyclic amines (HCAs) in cooked meats may play a role in colorectal cancer (CRC) development. Objectives: We aimed to prospectively examine the association between estimated intakes of HCAs and meat-derived ...

    • Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer 

      Hanyuda, Akiko; Kim, Sun A.; Martinez-Fernandez, Alejandro; Qian, Zhi Rong; Yamauchi, Mai; Nakashima, Reiko; Morikawa, Teppei; Liao, Xiaoyun; Inamura, Kentaro; Mima, Kosuke; Cao, Yin; Zhang, Xuehong; Wu, Kana; Chan, Andrew T.; Ogino, Shuji; Giovannucci, Edward; Meyerhardt, Jeffrey; Fuchs, Charles; Shivdasani, Ramesh (Springer Nature, 2015-11-17)
      Background. High-level physical activity is associated with lower colorectal cancer (CRC) mortality, likely through insulin sensitization. Insulin receptor substrate 1 (IRS1) is a mediator of insulin and insulin-like growth ...