Browsing by Author "Yuan, Hongyan"

Now showing items 1-4 of 4

    • Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy 

      Aratyn-Schaus, Yvonne; Pasqualini, Francesco S.; Yuan, Hongyan; McCain, Megan L.; Ye, George J.C.; Sheehy, Sean P.; Campbell, Patrick H.; Parker, Kevin Kit (The Rockefeller University Press, 2016)
      The efficacy of cardiac cell therapy depends on the integration of existing and newly formed cardiomyocytes. Here, we developed a minimal in vitro model of this interface by engineering two cell microtissues (μtissues) ...

    • Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing 

      Lind, Johan Ulrik; Busbee, Travis Alexander; Valentine, Alexander; Pasqualini, Francesco; Yuan, Hongyan; Yedid, Moran; Park, Sung-Jin; Kotikian, Arda; Nesmith, Alexander Peyton; Campbell, Patrick H.; Vlassak, Joost J.; Lewis, Jennifer; Parker, Kevin Kit (Springer Nature, 2016)
      Biomedical research has relied on animal studies and conventional cell cultures for decades. Recently, microphysiological systems (MPS), also known as organs-on-chips, that recapitulate the structure and function of native ...

    • Modeling the mitochondrial cardiomyopathy of Barth syndrome with iPSC and heart-on-chip technologies 

      Wang, Gang; McCain, Megan L.; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E.; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-zhi; Li, Kai; Wang, Jiwu; Wanders, Ronald J. A.; Kulik, Wim; Vaz, Frédéric M.; Laflamme, Michael A.; Murry, Charles E.; Chien, Kenneth R.; Kelley, Richard I.; Church, George M.; Parker, Kevin Kit; Pu, William T. (2014)
      Studying monogenic mitochondrial cardiomyopathies may yield insights into mitochondrial roles in cardiac development and disease. Here, we combine patient-derived and genetically engineered iPSCs with tissue engineering ...

    • Phototactic guidance of a tissue-engineered soft-robotic ray 

      Park, Sung-Jin; Gazzola, Mattia; Park, Kyung; Park, Shirley; Di Santo, Valentina; Blevins, Erin; Lind, Johan Ulrik; Campbell, Patrick Healy; Dauth, Stephanie; Capulli, Andrew Keith; Pasqualini, Francesco; Ahn, Seungkuk; Cho, Alexander; Yuan, Hongyan; Maoz, Ben Meir; Vijaykumar, Ragu; Choi, Jeong-Woo; Deisseroth, Karl; Lauder, George V.; Mahadevan, Lakshminarayanan; Parker, Kevin Kit (American Association for the Advancement of Science (AAAS), 2016)
      Inspired by the relatively simple morphological blueprint provided by batoid fish such as stingrays and skates, we create a biohybrid system that enables an artificial animal, a tissue-engineered ray, to swim and phototactically ...