Browsing by Author "Sadegh, Cameron"
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Directed differentiation of mouse embryonic stem cells into neocortical output neurons
Sadegh, Cameron (2013-10-18)During development of the neocortex, many diverse projection neuron subtypes are generated under regulation of cell-extrinsic and cell-intrinsic controls. One broad projection neuron class, corticofugal projection neurons ... -
Established Monolayer Differentiation of Mouse Embryonic Stem Cells Generates Heterogeneous Neocortical-Like Neurons Stalled at a Stage Equivalent to Midcorticogenesis
Sadegh, Cameron; Macklis, Jeffrey Daniel (Wiley-Blackwell, 2014)By assessing multiple positive and negative markers of forebrain progenitors and neurons, the authors show that now-standard, partially directed neocortical differentiation of mouse embryonic stem cells generates neurons ...