Browsing by Author "Franke, Molly"
Now showing items 1-14 of 14
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Aggressive Regimens for Multidrug-Resistant Tuberculosis Decrease All-Cause Mortality
Mitnick, Carole Diane; Franke, Molly Forrest; Rich, Michael Leonard; Alcantara Viru, Felix A.; Appleton, Sasha C.; Atwood, Sidney S.; Bayona, Jaime N.; Bonilla, Cesar A.; Chalco, Katiuska; Fraser, Hamish S. F.; Furin, Jennifer J.; Guerra, Dalia; Hurtado, Rocio M.; Joseph, Keith; Llaro, Karim; Mestanza, Lorena; Mukherjee, Joia S.; Muñoz, Maribel; Palacios, Eda; Sanchez, Epifanio; Seung, Kwonjune J.; Shin, Sonya S.; Sloutsky, Alexander; Tolman, Arielle W.; Becerra, Mercedes C. (Public Library of Science, 2013)Rationale: A better understanding of the composition of optimal treatment regimens for multidrug-resistant tuberculosis (MDR-TB) is essential for expanding universal access to effective treatment and for developing new ... -
Alcohol, Hospital Discharge, and Socioeconomic Risk Factors for Default from Multidrug Resistant Tuberculosis Treatment in Rural South Africa: A Retrospective Cohort Study
Kendall, Emily A.; Theron, Danie; Franke, Molly F.; van Helden, Paul; Victor, Thomas C.; Murray, Megan B.; Warren, Robin M.; Jacobson, Karen R. (Public Library of Science, 2013)Background: Default from multidrug-resistant tuberculosis (MDR-TB) treatment remains a major barrier to cure and epidemic control. We sought to identify patient risk factors for default from MDR-TB treatment and high-risk ... -
Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults
Matias, Wilfredo R.; Falkard, Brie; Charles, Richelle C.; Mayo-Smith, Leslie M.; Teng, Jessica E.; Xu, Peng; Kováč, Pavol; Ryan, Edward T.; Qadri, Firdausi; Franke, Molly F.; Ivers, Louise C.; Harris, Jason B. (Public Library of Science, 2016)Background: The bivalent whole-cell (BivWC) oral cholera vaccine (Shanchol) is effective in preventing cholera. However, evaluations of immune responses following vaccination with BivWC have been limited. To determine ... -
Cholera Vaccination Campaign Contributes to Improved Knowledge Regarding Cholera and Improved Practice Relevant to Waterborne Disease in Rural Haiti
Aibana, Omowunmi; Franke, Molly; Teng, Jessica; Hilaire, Johanne; Raymond, Max; Ivers, Louise C. (Public Library of Science, 2013)Background: Haiti's cholera epidemic has been devastating partly due to underlying weak infrastructure and limited clean water and sanitation. A comprehensive approach to cholera control is crucial, yet some have argued ... -
Discordant Treatment Responses to Combination Antiretroviral Therapy in Rwanda: A Prospective Cohort Study
Kayigamba, Felix R.; Franke, Molly F.; Bakker, Mirjam I.; Rodriguez, Carly A.; Bagiruwigize, Emmanuel; Wit, Ferdinand WNM; Rich, Michael L.; Schim van der Loeff, Maarten F. (Public Library of Science, 2016)Introduction: Some antiretroviral therapy naïve patients starting combination antiretroviral therapy (cART) experience a limited CD4 count rise despite virological suppression, or vice versa. We assessed the prevalence and ... -
Immunogenicity of a Killed Bivalent (O1 and O139) Whole Cell Oral Cholera Vaccine, Shanchol, in Haiti
Charles, Richelle C.; Hilaire, Isabelle J.; Mayo-Smith, Leslie M.; Teng, Jessica E.; Jerome, J. Gregory; Franke, Molly F.; Saha, Amit; Yu, Yanan; Kováč, Paul; Calderwood, Stephen B.; Ryan, Edward T.; LaRocque, Regina C.; Almazor, Charles P.; Qadri, Firdausi; Ivers, Louise C.; Harris, Jason B. (Public Library of Science, 2014)Background: Studies of the immunogenicity of the killed bivalent whole cell oral cholera vaccine, Shanchol, have been performed in historically cholera-endemic areas of Asia. There is a need to assess the immunogenicity ... -
Malaria Parasitemia and CD4 T Cell Count, Viral Load, and Adverse HIV Outcomes Among HIV-Infected Pregnant Women in Tanzania
Franke, Molly Forrest; Spiegelman, Donna Lynn; Ezeamama, A.; Aboud, S.; Msamanga, G. I.; Mehta, S.; Fawzi, Wafaie W. (American Society of Tropical Medicine and Hygiene, 2010)We examined the cross-sectional relationships between malaria parasitemia and CD4 T cell count and viral load among human immunodeficiency virus (HIV)-infected pregnant women. We then followed women to investigate whether ... -
Multidrug-Resistant Tuberculosis Treatment in North Korea: Is Scale-Up Possible?
Seung, Kwonjune J.; Franke, Molly; Linton, Stephen W. (Public Library of Science, 2016)Kwonjune Seung and colleagues describe the Eugene Bell Foundation's experience of treating MDR-TB in North Korea. -
Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru
Cohen, Ted; Murray, Megan Blanche; Abubakar, Ibrahim; Zhang, Zibiao; Sloutsky, Alexander; Arteaga, Fernando; Chalco, Katiuska; Franke, Molly Forrest; Becerra, Mercedes C. (Centers for Disease Control and Prevention, 2011)Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB ... -
Partner testing, linkage to care, and HIV-free survival in a program to prevent parent-to-child transmission of HIV in the Highlands of Papua New Guinea
Carmone, Andy; Bomai, Korai; Bongi, Wayaki; Frank, Tarua Dale; Dalepa, Huleve; Loifa, Betty; Kiromat, Mobumo; Das, Sarthak; Franke, Molly F. (Co-Action Publishing, 2014)Background: To eliminate new pediatric HIV infections, interventions that facilitate adherence, including those that minimize stigma, enhance social support, and mitigate the influence of poverty, will likely be required ... -
Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh
Falkard, Brie; Uddin, Taher; Arifur Rahman, M.; Franke, Molly F.; Aktar, Amena; Uddin, Muhammad Ikhtear; Bhuiyan, Taufiqur Rahman; Leung, Daniel T.; Charles, Richelle C.; Larocque, Regina C.; Harris, Jason B.; Calderwood, Stephen B.; Qadri, Firdausi; Ryan, Edward T. (The American Society of Tropical Medicine and Hygiene, 2015)Vibrio cholerae, the cause of cholera, induces both innate and adaptive immune responses in infected humans. Leptin is a hormone that plays a role in both metabolism and mediating immune responses. We characterized leptin ... -
Reduced Paediatric Hospitalizations for Malaria and Febrile Illness Patterns Following Implementation of Community-Based Malaria Control Programme in Rural Rwanda
Sievers, Amy Claire; Lewey, Jennifer; Musafiri, Placide; Franke, Molly Forrest; Bucyibaruta, Blaise J; Stulac, Sara Nicole; Rich, Michael Leonard; Karema, Corine; Daily, Johanna P (BioMed Central, 2008)Background: Malaria control is currently receiving significant international commitment. As part of this commitment, Rwanda has undertaken a two-pronged approach to combating malaria via mass distribution of long-lasting ... -
Time to Culture Conversion and Regimen Composition in Multidrug-Resistant Tuberculosis Treatment
Tierney, Dylan B.; Franke, Molly F.; Becerra, Mercedes C.; Alcántara Virú, Félix A.; Bonilla, César A.; Sánchez, Epifanio; Guerra, Dalia; Muñoz, Maribel; Llaro, Karim; Palacios, Eda; Mestanza, Lorena; Hurtado, Rocío M.; Furin, Jennifer J.; Shin, Sonya; Mitnick, Carole D. (Public Library of Science, 2014)Sputum cultures are an important tool in monitoring the response to tuberculosis treatment, especially in multidrug-resistant tuberculosis. There has, however, been little study of the effect of treatment regimen composition ... -
User Perceptions of an mHealth Medicine Dosing Tool for Community Health Workers
Palazuelos, Daniel; Diallo, Assiatou; Palazuelos, Lindsay; Payne, Jonathan; Franke, Molly Forrest (Journal of Medical Internet Research, 2014)