Now showing items 1-3 of 3

    • The Limits of Linked Suppression for Regulatory T Cells 

      Ito, Toshiro; Yamada, Akira; Batal, Ibrahim; Yeung, Melissa Y.; McGrath, Martina M.; Sayegh, Mohamed H.; Chandraker, Anil; Ueno, Takuya (Frontiers Media S.A., 2016)
      Background: We have previously found that CD4+CD25+ regulatory T cells (Tregs) can adoptively transfer tolerance after its induction with costimulatory blockade in a mouse model of murine cardiac allograft transplantation. ...
    • Live Images of Donor Dendritic Cells Trafficking via CX3CR1 Pathway 

      Ueno, Takuya; Kim, Pilhan; McGrath, Martina M.; Yeung, Melissa Y.; Shimizu, Tetsunosuke; Jung, Keehoon; Sayegh, Mohamed H.; Chandraker, Anil K.; Abdi, Reza; Yun, Seok H. (Frontiers Media S.A., 2016)
      Background: A number of studies have demonstrated the role of CX3CR1 in regulating the migration of monocytes into peripheral tissue and their transformation into dendritic cell (DC). No data are yet available on the ...
    • Prolonged, Low-Dose Anti-Thymocyte Globulin, Combined with CTLA4-Ig, Promotes Engraftment in a Stringent Transplant Model 

      D’Addio, Francesca; Boenisch, Olaf; Magee, Ciara N; Yeung, Melissa; Yuan, Xueli; Mfarrej, Bechara; Vergani, Andrea; Ansari, Mohammed Javeed; Fiorina, Paolo; Najafian, Nader (Public Library of Science, 2013)
      Background: Despite significant nephrotoxicity, calcineurin inhibitors (CNIs) remain the cornerstone of immunosuppression in solid organ transplantation. We, along with others, have reported tolerogenic properties of ...